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Rat fighting behavior: serum dopamine- -hydroxylase and hypothalamic tyrosine hydroxylase.

Publication ,  Journal Article
Lamprecht, F; Eichelman, B; Thoa, NB; Williams, RB; Kopin, IJ
Published in: Science
September 29, 1972

Male Sprague-Dawley rats were subjected to 4 weeks of daily periods of immobilization stress. One of two experimental groups was allowed 1 month of recovery. After 4 weeks of stress, there was a significant increase in shockinduced fighting, in the activity of serum dopamine-beta-hydroxylase, and in the activity of hypothalamic tyrosine hydroxylase. The concentration of hypothalamic norepinephrine was not decreased. After 4 weeks of recovery, only serum dopamine-betahydroxylase activity returned to normal; it therefore appears that longterm stress may increase central catecholamine synthesis. possibly resulting in a persistent increase in aggressive behavior.

Duke Scholars

Published In

Science

DOI

ISSN

0036-8075

Publication Date

September 29, 1972

Volume

177

Issue

4055

Start / End Page

1214 / 1215

Location

United States

Related Subject Headings

  • Tyrosine 3-Monooxygenase
  • Tyrosine
  • Time Factors
  • Stress, Psychological
  • Rats
  • Norepinephrine
  • Mixed Function Oxygenases
  • Male
  • Immobilization
  • Hypothalamus
 

Citation

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Lamprecht, F., Eichelman, B., Thoa, N. B., Williams, R. B., & Kopin, I. J. (1972). Rat fighting behavior: serum dopamine- -hydroxylase and hypothalamic tyrosine hydroxylase. Science, 177(4055), 1214–1215. https://doi.org/10.1126/science.177.4055.1214
Lamprecht, F., B. Eichelman, N. B. Thoa, R. B. Williams, and I. J. Kopin. “Rat fighting behavior: serum dopamine- -hydroxylase and hypothalamic tyrosine hydroxylase.Science 177, no. 4055 (September 29, 1972): 1214–15. https://doi.org/10.1126/science.177.4055.1214.
Lamprecht F, Eichelman B, Thoa NB, Williams RB, Kopin IJ. Rat fighting behavior: serum dopamine- -hydroxylase and hypothalamic tyrosine hydroxylase. Science. 1972 Sep 29;177(4055):1214–5.
Lamprecht, F., et al. “Rat fighting behavior: serum dopamine- -hydroxylase and hypothalamic tyrosine hydroxylase.Science, vol. 177, no. 4055, Sept. 1972, pp. 1214–15. Pubmed, doi:10.1126/science.177.4055.1214.
Lamprecht F, Eichelman B, Thoa NB, Williams RB, Kopin IJ. Rat fighting behavior: serum dopamine- -hydroxylase and hypothalamic tyrosine hydroxylase. Science. 1972 Sep 29;177(4055):1214–1215.
Journal cover image

Published In

Science

DOI

ISSN

0036-8075

Publication Date

September 29, 1972

Volume

177

Issue

4055

Start / End Page

1214 / 1215

Location

United States

Related Subject Headings

  • Tyrosine 3-Monooxygenase
  • Tyrosine
  • Time Factors
  • Stress, Psychological
  • Rats
  • Norepinephrine
  • Mixed Function Oxygenases
  • Male
  • Immobilization
  • Hypothalamus