A mediator lost in the war on cancer.
Publication
, Journal Article
Guo, X; Wang, X-F
Published in: Cell
November 21, 2012
An unexpected role for a Mediator subunit, MED12, in resistance to multiple anticancer agents is revealed by Huang et al. Loss of MED12 confers drug resistance by activating transforming growth factor b (TGF-b) signaling. Inhibition of the TGF-b pathway resensitizes cells to therapeutic drugs, suggesting a new combinatorial cancer treatment.
Duke Scholars
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Published In
Cell
DOI
EISSN
1097-4172
Publication Date
November 21, 2012
Volume
151
Issue
5
Start / End Page
927 / 929
Location
United States
Related Subject Headings
- Developmental Biology
- 32 Biomedical and clinical sciences
- 31 Biological sciences
- 11 Medical and Health Sciences
- 06 Biological Sciences
Citation
APA
Chicago
ICMJE
MLA
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Guo, X., & Wang, X.-F. (2012). A mediator lost in the war on cancer. Cell, 151(5), 927–929. https://doi.org/10.1016/j.cell.2012.11.003
Guo, Xing, and Xiao-Fan Wang. “A mediator lost in the war on cancer.” Cell 151, no. 5 (November 21, 2012): 927–29. https://doi.org/10.1016/j.cell.2012.11.003.
Guo X, Wang X-F. A mediator lost in the war on cancer. Cell. 2012 Nov 21;151(5):927–9.
Guo, Xing, and Xiao-Fan Wang. “A mediator lost in the war on cancer.” Cell, vol. 151, no. 5, Nov. 2012, pp. 927–29. Pubmed, doi:10.1016/j.cell.2012.11.003.
Guo X, Wang X-F. A mediator lost in the war on cancer. Cell. 2012 Nov 21;151(5):927–929.
Published In
Cell
DOI
EISSN
1097-4172
Publication Date
November 21, 2012
Volume
151
Issue
5
Start / End Page
927 / 929
Location
United States
Related Subject Headings
- Developmental Biology
- 32 Biomedical and clinical sciences
- 31 Biological sciences
- 11 Medical and Health Sciences
- 06 Biological Sciences