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Effects of electroconvulsive therapy in adolescents with severe endogenous depression resistant to pharmacotherapy.

Publication ,  Journal Article
Strober, M; Rao, U; DeAntonio, M; Liston, E; State, M; Amaya-Jackson, L; Latz, S
Published in: Biol Psychiatry
March 1, 1998

BACKGROUND: This open, prospective study examined the effects of electroconvulsive therapy (ECT) in 10 adolescents with primary, endogenous, psychotic depression who were resistant to antidepressant pharmacotherapy. METHODS: Change in symptom severity from baseline was assessed weekly with Hamilton Depression Rating Scale (HDRS) ratings, and outcome was measured additionally at 1 month, and again at 1 year, post-ECT. RESULTS: All but 1 patient demonstrated dramatic improvement, with statistically significant decreases in mean HDRS score detected after the first week of treatment. All responders maintained the benefits of their treatment. CONCLUSIONS: The results provide evidence of the clinical effectiveness of ECT in adolescents with phenomenological characteristics shown to be predictive of ECT response in adults.

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Published In

Biol Psychiatry

DOI

ISSN

0006-3223

Publication Date

March 1, 1998

Volume

43

Issue

5

Start / End Page

335 / 338

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Psychiatry
  • Psychiatric Status Rating Scales
  • Prospective Studies
  • Male
  • Longitudinal Studies
  • Humans
  • Follow-Up Studies
  • Female
  • Electroconvulsive Therapy
 

Citation

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Strober, M., Rao, U., DeAntonio, M., Liston, E., State, M., Amaya-Jackson, L., & Latz, S. (1998). Effects of electroconvulsive therapy in adolescents with severe endogenous depression resistant to pharmacotherapy. Biol Psychiatry, 43(5), 335–338. https://doi.org/10.1016/s0006-3223(97)00205-9
Strober, M., U. Rao, M. DeAntonio, E. Liston, M. State, L. Amaya-Jackson, and S. Latz. “Effects of electroconvulsive therapy in adolescents with severe endogenous depression resistant to pharmacotherapy.Biol Psychiatry 43, no. 5 (March 1, 1998): 335–38. https://doi.org/10.1016/s0006-3223(97)00205-9.
Strober M, Rao U, DeAntonio M, Liston E, State M, Amaya-Jackson L, et al. Effects of electroconvulsive therapy in adolescents with severe endogenous depression resistant to pharmacotherapy. Biol Psychiatry. 1998 Mar 1;43(5):335–8.
Strober, M., et al. “Effects of electroconvulsive therapy in adolescents with severe endogenous depression resistant to pharmacotherapy.Biol Psychiatry, vol. 43, no. 5, Mar. 1998, pp. 335–38. Pubmed, doi:10.1016/s0006-3223(97)00205-9.
Strober M, Rao U, DeAntonio M, Liston E, State M, Amaya-Jackson L, Latz S. Effects of electroconvulsive therapy in adolescents with severe endogenous depression resistant to pharmacotherapy. Biol Psychiatry. 1998 Mar 1;43(5):335–338.
Journal cover image

Published In

Biol Psychiatry

DOI

ISSN

0006-3223

Publication Date

March 1, 1998

Volume

43

Issue

5

Start / End Page

335 / 338

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Psychiatry
  • Psychiatric Status Rating Scales
  • Prospective Studies
  • Male
  • Longitudinal Studies
  • Humans
  • Follow-Up Studies
  • Female
  • Electroconvulsive Therapy