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Neuropsychiatric applications of transcranial magnetic stimulation: a meta analysis.

Publication ,  Journal Article
Burt, T; Lisanby, SH; Sackeim, HA
Published in: Int J Neuropsychopharmacol
March 2002

Transcranial magnetic stimulation (TMS) is a technology that allows for non-invasive modulation of the excitability and function of discrete brain cortical areas. TMS uses alternating magnetic fields to induce electric currents in cortical tissue. In psychiatry, TMS has been studied primarily as a potential treatment for major depression. Most studies indicate that slow-frequency repetitive TMS (rTMS) and higher frequency rTMS have antidepressant properties. A meta-analysis of controlled studies indicates that this effect is fairly robust from a statistical viewpoint. However, effect sizes are heterogeneous, and few studies have shown that rTMS results in substantial rates of clinical response or remission, and the durability of antidepressant effects is largely unknown. We review in detail rTMS studies in the treatment of depression, as well as summarize treatment studies of mania, obsessive-compulsive disorder, post-traumatic stress disorder, and schizophrenia. We also review the application of TMS in the study of the pathophysiology of psychiatric disorders and summarize studies of the safety of TMS in human subjects.

Duke Scholars

Published In

Int J Neuropsychopharmacol

DOI

ISSN

1461-1457

Publication Date

March 2002

Volume

5

Issue

1

Start / End Page

73 / 103

Location

England

Related Subject Headings

  • Sleep
  • Psychiatry
  • Personality
  • Neurosecretory Systems
  • Mental Disorders
  • Humans
  • Electromagnetic Fields
  • Depressive Disorder, Major
  • Cognition
  • Cerebrovascular Circulation
 

Citation

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Burt, T., Lisanby, S. H., & Sackeim, H. A. (2002). Neuropsychiatric applications of transcranial magnetic stimulation: a meta analysis. Int J Neuropsychopharmacol, 5(1), 73–103. https://doi.org/10.1017/S1461145702002791
Burt, Tal, Sarah H. Lisanby, and Harold A. Sackeim. “Neuropsychiatric applications of transcranial magnetic stimulation: a meta analysis.Int J Neuropsychopharmacol 5, no. 1 (March 2002): 73–103. https://doi.org/10.1017/S1461145702002791.
Burt T, Lisanby SH, Sackeim HA. Neuropsychiatric applications of transcranial magnetic stimulation: a meta analysis. Int J Neuropsychopharmacol. 2002 Mar;5(1):73–103.
Burt, Tal, et al. “Neuropsychiatric applications of transcranial magnetic stimulation: a meta analysis.Int J Neuropsychopharmacol, vol. 5, no. 1, Mar. 2002, pp. 73–103. Pubmed, doi:10.1017/S1461145702002791.
Burt T, Lisanby SH, Sackeim HA. Neuropsychiatric applications of transcranial magnetic stimulation: a meta analysis. Int J Neuropsychopharmacol. 2002 Mar;5(1):73–103.
Journal cover image

Published In

Int J Neuropsychopharmacol

DOI

ISSN

1461-1457

Publication Date

March 2002

Volume

5

Issue

1

Start / End Page

73 / 103

Location

England

Related Subject Headings

  • Sleep
  • Psychiatry
  • Personality
  • Neurosecretory Systems
  • Mental Disorders
  • Humans
  • Electromagnetic Fields
  • Depressive Disorder, Major
  • Cognition
  • Cerebrovascular Circulation