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Liver and intestine transplantation in the United States 1998-2007.

Publication ,  Journal Article
Berg, CL; Steffick, DE; Edwards, EB; Heimbach, JK; Magee, JC; Washburn, WK; Mazariegos, GV
Published in: Am J Transplant
April 2009

Liver transplantation numbers in the United States remained constant from 2004 to 2007, while the number of waiting list candidates has trended down. In 2007, the waiting list was at its smallest since 1999, with adults > or =50 years representing the majority of candidates. Noncholestatic cirrhosis was most commonly diagnosed. Most age groups had decreased waiting list death rates; however, children <1 year had the highest death rate. Use of liver allografts from donation after cardiac death (DCD) donors increased in 2007. Model for end-stage liver disease (MELD)/pediatric model for end-stage liver disease (PELD) scores have changed very little since 2002, with MELD/PELD <15 accounting for 75% of the waiting list. Over the same period, the number of transplants for MELD/PELD <15 decreased from 16.4% to 9.8%. Hepatocellular carcinoma exceptions increased slightly. The intestine transplantation waiting list decreased from 2006, with the majority of candidates being children <5 years old. Death rates improved, but remain unacceptably high. Policy changes have been implemented to improve allocation and recovery of intestine grafts to positively impact mortality. In addition to evaluating trends in liver and intestine transplantation, we review in depth, issues related to organ acceptance rates, DCD, living donor transplantation and MELD/PELD exceptions.

Duke Scholars

Published In

Am J Transplant

DOI

EISSN

1600-6143

Publication Date

April 2009

Volume

9

Issue

4 Pt 2

Start / End Page

907 / 931

Location

United States

Related Subject Headings

  • Waiting Lists
  • United States
  • Transplantation, Homologous
  • Survivors
  • Survival Rate
  • Surgery
  • Racial Groups
  • Male
  • Liver Transplantation
  • Liver Neoplasms
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Berg, C. L., Steffick, D. E., Edwards, E. B., Heimbach, J. K., Magee, J. C., Washburn, W. K., & Mazariegos, G. V. (2009). Liver and intestine transplantation in the United States 1998-2007. Am J Transplant, 9(4 Pt 2), 907–931. https://doi.org/10.1111/j.1600-6143.2009.02567.x
Berg, C. L., D. E. Steffick, E. B. Edwards, J. K. Heimbach, J. C. Magee, W. K. Washburn, and G. V. Mazariegos. “Liver and intestine transplantation in the United States 1998-2007.Am J Transplant 9, no. 4 Pt 2 (April 2009): 907–31. https://doi.org/10.1111/j.1600-6143.2009.02567.x.
Berg CL, Steffick DE, Edwards EB, Heimbach JK, Magee JC, Washburn WK, et al. Liver and intestine transplantation in the United States 1998-2007. Am J Transplant. 2009 Apr;9(4 Pt 2):907–31.
Berg, C. L., et al. “Liver and intestine transplantation in the United States 1998-2007.Am J Transplant, vol. 9, no. 4 Pt 2, Apr. 2009, pp. 907–31. Pubmed, doi:10.1111/j.1600-6143.2009.02567.x.
Berg CL, Steffick DE, Edwards EB, Heimbach JK, Magee JC, Washburn WK, Mazariegos GV. Liver and intestine transplantation in the United States 1998-2007. Am J Transplant. 2009 Apr;9(4 Pt 2):907–931.
Journal cover image

Published In

Am J Transplant

DOI

EISSN

1600-6143

Publication Date

April 2009

Volume

9

Issue

4 Pt 2

Start / End Page

907 / 931

Location

United States

Related Subject Headings

  • Waiting Lists
  • United States
  • Transplantation, Homologous
  • Survivors
  • Survival Rate
  • Surgery
  • Racial Groups
  • Male
  • Liver Transplantation
  • Liver Neoplasms