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Severe cholestasis related to intraconazole for the treatment of onychomycosis.

Publication ,  Journal Article
Talwalkar, JA; Soetikno, RE; Carr-Locke, DL; Berg, CL
Published in: Am J Gastroenterol
December 1999

We describe a case of prolonged cholestasis temporally associated with the use of itraconazole for onychomycosis. Peak bilirubin level of 32.0 mg/dl was documented approximately 2 months after discontinuation of the patient's itraconazole therapy, with symptoms of cholestasis persisting more than 1 month after the peak in bilirubin. Physicians should be aware of the potential for severe cholestasis associated with itraconazole usage.

Duke Scholars

Published In

Am J Gastroenterol

DOI

ISSN

0002-9270

Publication Date

December 1999

Volume

94

Issue

12

Start / End Page

3632 / 3633

Location

United States

Related Subject Headings

  • Onychomycosis
  • Male
  • Liver Function Tests
  • Itraconazole
  • Humans
  • Gastroenterology & Hepatology
  • Cholestasis, Intrahepatic
  • Bilirubin
  • Antifungal Agents
  • Aged
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Talwalkar, J. A., Soetikno, R. E., Carr-Locke, D. L., & Berg, C. L. (1999). Severe cholestasis related to intraconazole for the treatment of onychomycosis. Am J Gastroenterol, 94(12), 3632–3633. https://doi.org/10.1111/j.1572-0241.1999.01623.x
Talwalkar, J. A., R. E. Soetikno, D. L. Carr-Locke, and C. L. Berg. “Severe cholestasis related to intraconazole for the treatment of onychomycosis.Am J Gastroenterol 94, no. 12 (December 1999): 3632–33. https://doi.org/10.1111/j.1572-0241.1999.01623.x.
Talwalkar JA, Soetikno RE, Carr-Locke DL, Berg CL. Severe cholestasis related to intraconazole for the treatment of onychomycosis. Am J Gastroenterol. 1999 Dec;94(12):3632–3.
Talwalkar, J. A., et al. “Severe cholestasis related to intraconazole for the treatment of onychomycosis.Am J Gastroenterol, vol. 94, no. 12, Dec. 1999, pp. 3632–33. Pubmed, doi:10.1111/j.1572-0241.1999.01623.x.
Talwalkar JA, Soetikno RE, Carr-Locke DL, Berg CL. Severe cholestasis related to intraconazole for the treatment of onychomycosis. Am J Gastroenterol. 1999 Dec;94(12):3632–3633.
Journal cover image

Published In

Am J Gastroenterol

DOI

ISSN

0002-9270

Publication Date

December 1999

Volume

94

Issue

12

Start / End Page

3632 / 3633

Location

United States

Related Subject Headings

  • Onychomycosis
  • Male
  • Liver Function Tests
  • Itraconazole
  • Humans
  • Gastroenterology & Hepatology
  • Cholestasis, Intrahepatic
  • Bilirubin
  • Antifungal Agents
  • Aged