
Severe cholestasis related to intraconazole for the treatment of onychomycosis.
Publication
, Journal Article
Talwalkar, JA; Soetikno, RE; Carr-Locke, DL; Berg, CL
Published in: Am J Gastroenterol
December 1999
We describe a case of prolonged cholestasis temporally associated with the use of itraconazole for onychomycosis. Peak bilirubin level of 32.0 mg/dl was documented approximately 2 months after discontinuation of the patient's itraconazole therapy, with symptoms of cholestasis persisting more than 1 month after the peak in bilirubin. Physicians should be aware of the potential for severe cholestasis associated with itraconazole usage.
Duke Scholars
Published In
Am J Gastroenterol
DOI
ISSN
0002-9270
Publication Date
December 1999
Volume
94
Issue
12
Start / End Page
3632 / 3633
Location
United States
Related Subject Headings
- Onychomycosis
- Male
- Liver Function Tests
- Itraconazole
- Humans
- Gastroenterology & Hepatology
- Cholestasis, Intrahepatic
- Bilirubin
- Antifungal Agents
- Aged
Citation
APA
Chicago
ICMJE
MLA
NLM
Talwalkar, J. A., Soetikno, R. E., Carr-Locke, D. L., & Berg, C. L. (1999). Severe cholestasis related to intraconazole for the treatment of onychomycosis. Am J Gastroenterol, 94(12), 3632–3633. https://doi.org/10.1111/j.1572-0241.1999.01623.x
Talwalkar, J. A., R. E. Soetikno, D. L. Carr-Locke, and C. L. Berg. “Severe cholestasis related to intraconazole for the treatment of onychomycosis.” Am J Gastroenterol 94, no. 12 (December 1999): 3632–33. https://doi.org/10.1111/j.1572-0241.1999.01623.x.
Talwalkar JA, Soetikno RE, Carr-Locke DL, Berg CL. Severe cholestasis related to intraconazole for the treatment of onychomycosis. Am J Gastroenterol. 1999 Dec;94(12):3632–3.
Talwalkar, J. A., et al. “Severe cholestasis related to intraconazole for the treatment of onychomycosis.” Am J Gastroenterol, vol. 94, no. 12, Dec. 1999, pp. 3632–33. Pubmed, doi:10.1111/j.1572-0241.1999.01623.x.
Talwalkar JA, Soetikno RE, Carr-Locke DL, Berg CL. Severe cholestasis related to intraconazole for the treatment of onychomycosis. Am J Gastroenterol. 1999 Dec;94(12):3632–3633.

Published In
Am J Gastroenterol
DOI
ISSN
0002-9270
Publication Date
December 1999
Volume
94
Issue
12
Start / End Page
3632 / 3633
Location
United States
Related Subject Headings
- Onychomycosis
- Male
- Liver Function Tests
- Itraconazole
- Humans
- Gastroenterology & Hepatology
- Cholestasis, Intrahepatic
- Bilirubin
- Antifungal Agents
- Aged