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How should we measure and report radiotherapy-induced xerostomia?

Publication ,  Journal Article
Eisbruch, A; Rhodus, N; Rosenthal, D; Murphy, B; Rasch, C; Sonis, S; Scarantino, C; Brizel, D
Published in: Semin Radiat Oncol
July 2003

Xerostomia is commonly measured and graded using objective measures of major salivary gland output and observer-rated toxicity grading. The separation between the different grades is somewhat ambiguous in the current toxicity grading systems. We propose a new grading system based primarily on the functional deficits associated with xerostomia. Salivary flow rates have been added as a criterion to the grading system, notwithstanding the weak correlation reported in most studies between the symptoms and objective functional measures. In addition to the observer-rated toxicity grading, recording of patient-reported quality of life, using validated instruments, is encouraged.

Duke Scholars

Published In

Semin Radiat Oncol

DOI

ISSN

1053-4296

Publication Date

July 2003

Volume

13

Issue

3

Start / End Page

226 / 234

Location

United States

Related Subject Headings

  • Xerostomia
  • Salivary Glands
  • Radiotherapy
  • Radionuclide Imaging
  • Radiation Injuries
  • Quality of Life
  • Oncology & Carcinogenesis
  • Humans
  • Head and Neck Neoplasms
  • 3211 Oncology and carcinogenesis
 

Citation

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ICMJE
MLA
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Eisbruch, A., Rhodus, N., Rosenthal, D., Murphy, B., Rasch, C., Sonis, S., … Brizel, D. (2003). How should we measure and report radiotherapy-induced xerostomia? Semin Radiat Oncol, 13(3), 226–234. https://doi.org/10.1016/S1053-4296(03)00033-X
Eisbruch, Avraham, Nelson Rhodus, David Rosenthal, Barbara Murphy, Coen Rasch, Stephen Sonis, Charles Scarantino, and David Brizel. “How should we measure and report radiotherapy-induced xerostomia?Semin Radiat Oncol 13, no. 3 (July 2003): 226–34. https://doi.org/10.1016/S1053-4296(03)00033-X.
Eisbruch A, Rhodus N, Rosenthal D, Murphy B, Rasch C, Sonis S, et al. How should we measure and report radiotherapy-induced xerostomia? Semin Radiat Oncol. 2003 Jul;13(3):226–34.
Eisbruch, Avraham, et al. “How should we measure and report radiotherapy-induced xerostomia?Semin Radiat Oncol, vol. 13, no. 3, July 2003, pp. 226–34. Pubmed, doi:10.1016/S1053-4296(03)00033-X.
Eisbruch A, Rhodus N, Rosenthal D, Murphy B, Rasch C, Sonis S, Scarantino C, Brizel D. How should we measure and report radiotherapy-induced xerostomia? Semin Radiat Oncol. 2003 Jul;13(3):226–234.
Journal cover image

Published In

Semin Radiat Oncol

DOI

ISSN

1053-4296

Publication Date

July 2003

Volume

13

Issue

3

Start / End Page

226 / 234

Location

United States

Related Subject Headings

  • Xerostomia
  • Salivary Glands
  • Radiotherapy
  • Radionuclide Imaging
  • Radiation Injuries
  • Quality of Life
  • Oncology & Carcinogenesis
  • Humans
  • Head and Neck Neoplasms
  • 3211 Oncology and carcinogenesis