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Gonad morphogenesis in vertebrates: divergent means to a convergent end.

Publication ,  Journal Article
DeFalco, T; Capel, B
Published in: Annu Rev Cell Dev Biol
2009

A critical element of successful sexual reproduction is the generation of sexually dimorphic adult reproductive organs, the testis and ovary, which produce functional gametes. Examination of different vertebrate species shows that the adult gonad is remarkably similar in its morphology across different phylogenetic classes. Surprisingly, however, the cellular and molecular programs employed to create similar organs are not evolutionarily conserved. We highlight the mechanisms used by different vertebrate model systems to generate the somatic architecture necessary to support gametogenesis. In addition, we examine the different vertebrate patterns of germ cell migration from their site of origin to colonize the gonad and highlight their roles in sex-specific morphogenesis. We also discuss the plasticity of the adult gonad and consider how different genetic and environmental conditions can induce transitions between testis and ovary morphology.

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Published In

Annu Rev Cell Dev Biol

DOI

EISSN

1530-8995

Publication Date

2009

Volume

25

Start / End Page

457 / 482

Location

United States

Related Subject Headings

  • Vertebrates
  • Testis
  • Sex Differentiation
  • Ovary
  • Morphogenesis
  • Male
  • Humans
  • Gene Expression Regulation, Developmental
  • Female
  • Developmental Biology
 

Citation

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DeFalco, T., & Capel, B. (2009). Gonad morphogenesis in vertebrates: divergent means to a convergent end. Annu Rev Cell Dev Biol, 25, 457–482. https://doi.org/10.1146/annurev.cellbio.042308.13350
DeFalco, Tony, and Blanche Capel. “Gonad morphogenesis in vertebrates: divergent means to a convergent end.Annu Rev Cell Dev Biol 25 (2009): 457–82. https://doi.org/10.1146/annurev.cellbio.042308.13350.
DeFalco T, Capel B. Gonad morphogenesis in vertebrates: divergent means to a convergent end. Annu Rev Cell Dev Biol. 2009;25:457–82.
DeFalco, Tony, and Blanche Capel. “Gonad morphogenesis in vertebrates: divergent means to a convergent end.Annu Rev Cell Dev Biol, vol. 25, 2009, pp. 457–82. Pubmed, doi:10.1146/annurev.cellbio.042308.13350.
DeFalco T, Capel B. Gonad morphogenesis in vertebrates: divergent means to a convergent end. Annu Rev Cell Dev Biol. 2009;25:457–482.

Published In

Annu Rev Cell Dev Biol

DOI

EISSN

1530-8995

Publication Date

2009

Volume

25

Start / End Page

457 / 482

Location

United States

Related Subject Headings

  • Vertebrates
  • Testis
  • Sex Differentiation
  • Ovary
  • Morphogenesis
  • Male
  • Humans
  • Gene Expression Regulation, Developmental
  • Female
  • Developmental Biology