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Prediction of differential adult health burden by conduct problem subtypes in males.

Publication ,  Journal Article
Odgers, CL; Caspi, A; Broadbent, JM; Dickson, N; Hancox, RJ; Harrington, H; Poulton, R; Sears, MR; Thomson, WM; Moffitt, TE
Published in: Archives of general psychiatry
April 2007

A cardinal feature of the DSM-IV diagnostic criteria for conduct disorder is the distinction between childhood- vs adolescent-onset subtypes. Whether such developmental subtypes exist in the population and have different prognoses should be rigorously tested to inform the DSM-V.To evaluate the epidemiological validity of childhood- vs adolescent-onset conduct problems in a prospective birth cohort, and to assess whether life-course-persistent conduct problems are associated with a greater adult health burden.Our sample includes 526 male study members in the Dunedin Multidisciplinary Health and Development Study, a 1-year birth cohort (April 1, 1972, through March 30, 1973). Developmental trajectories were defined using prospective ratings of conduct problems at 7, 9, 11, 13, 15, 18, 21, and 26 years of age.Health burden was assessed as mental and physical health problems at 32 years of age measured via diagnostic interviews and physical examinations.We identified the following 4 developmental subtypes of conduct problems through general growth mixture modeling: (1) childhood-onset/life-course-persistent, (2) adolescent onset, (3) childhood limited, and (4) low. At 32 years of age, study members with the life-course-persistent subtype experienced the worst health burden. To a lesser extent, those with the adolescent-onset subtype also experienced health problems. A childhood-limited subtype not specified by DSM-IV was revealed; its adult health outcomes were within the range of the cohort norm.Results support the epidemiological validity of the DSM-IV conduct disorder distinction based on age of onset but highlight the need to also consider long-term persistence to refine diagnosis. Preventing and treating conduct problems has the potential to reduce the adult health burden.

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Published In

Archives of general psychiatry

DOI

EISSN

1538-3636

ISSN

0003-990X

Publication Date

April 2007

Volume

64

Issue

4

Start / End Page

476 / 484

Related Subject Headings

  • Sex Factors
  • Risk Factors
  • Reproducibility of Results
  • Psychiatry
  • Psychiatric Status Rating Scales
  • Prospective Studies
  • Prognosis
  • Prevalence
  • Physical Examination
  • Outcome Assessment, Health Care
 

Citation

APA
Chicago
ICMJE
MLA
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Odgers, C. L., Caspi, A., Broadbent, J. M., Dickson, N., Hancox, R. J., Harrington, H., … Moffitt, T. E. (2007). Prediction of differential adult health burden by conduct problem subtypes in males. Archives of General Psychiatry, 64(4), 476–484. https://doi.org/10.1001/archpsyc.64.4.476
Odgers, Candice L., Avshalom Caspi, Jonathan M. Broadbent, Nigel Dickson, Robert J. Hancox, Honalee Harrington, Richie Poulton, Malcolm R. Sears, W Murray Thomson, and Terrie E. Moffitt. “Prediction of differential adult health burden by conduct problem subtypes in males.Archives of General Psychiatry 64, no. 4 (April 2007): 476–84. https://doi.org/10.1001/archpsyc.64.4.476.
Odgers CL, Caspi A, Broadbent JM, Dickson N, Hancox RJ, Harrington H, et al. Prediction of differential adult health burden by conduct problem subtypes in males. Archives of general psychiatry. 2007 Apr;64(4):476–84.
Odgers, Candice L., et al. “Prediction of differential adult health burden by conduct problem subtypes in males.Archives of General Psychiatry, vol. 64, no. 4, Apr. 2007, pp. 476–84. Epmc, doi:10.1001/archpsyc.64.4.476.
Odgers CL, Caspi A, Broadbent JM, Dickson N, Hancox RJ, Harrington H, Poulton R, Sears MR, Thomson WM, Moffitt TE. Prediction of differential adult health burden by conduct problem subtypes in males. Archives of general psychiatry. 2007 Apr;64(4):476–484.

Published In

Archives of general psychiatry

DOI

EISSN

1538-3636

ISSN

0003-990X

Publication Date

April 2007

Volume

64

Issue

4

Start / End Page

476 / 484

Related Subject Headings

  • Sex Factors
  • Risk Factors
  • Reproducibility of Results
  • Psychiatry
  • Psychiatric Status Rating Scales
  • Prospective Studies
  • Prognosis
  • Prevalence
  • Physical Examination
  • Outcome Assessment, Health Care