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Relative impact of maternal depression and associated risk factors on offspring psychopathology.

Publication ,  Journal Article
Barker, ED; Copeland, W; Maughan, B; Jaffee, SR; Uher, R
Published in: Br J Psychiatry
February 2012

BACKGROUND: In general, mothers with depression experience more environmental and family risk factors, and lead riskier lifestyles, than mothers who are not depressed. AIMS: To test whether the exposure of a child to risk factors associated with mental health adds to the prediction of child psychopathology beyond exposure to maternal depression. METHOD: In 7429 mother-offspring pairs participating in the Avon Longitudinal Study of Parents and Children in the UK, maternal depression was assessed when the children were aged 1.5 years; multiple risk factor exposures were examined between birth and 2 years of age; and DSM-IV-based externalising and internalising diagnoses were evaluated when the children were 7.5 years of age. RESULTS: Children of clinically depressed mothers were exposed to more risk factors associated with maternal mental health. Maternal depression increased diagnoses of externalising and internalising disorders, but a substantial portion of these associations was explained by increased risk factor exposure (41% for externalising and 37% for internalising disorders). At the same time, these risk exposures significantly increased the odds of both externalising and internalising diagnoses, over and above the influence of maternal depression. CONCLUSIONS: Children of clinically depressed mothers are exposed to both maternal psychopathology and risks that are associated with maternal mental health. These results may explain why treating mothers with depression shows beneficial effects for children, but does not completely neutralise the increased risk of psychopathology and impairment.

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Published In

Br J Psychiatry

DOI

EISSN

1472-1465

Publication Date

February 2012

Volume

200

Issue

2

Start / End Page

124 / 129

Location

England

Related Subject Headings

  • Young Adult
  • Socioeconomic Factors
  • Social Support
  • Social Environment
  • Psychiatry
  • Psychiatric Status Rating Scales
  • Pregnancy
  • Mothers
  • Mother-Child Relations
  • Male
 

Citation

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ICMJE
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Barker, E. D., Copeland, W., Maughan, B., Jaffee, S. R., & Uher, R. (2012). Relative impact of maternal depression and associated risk factors on offspring psychopathology. Br J Psychiatry, 200(2), 124–129. https://doi.org/10.1192/bjp.bp.111.092346
Barker, Edward D., William Copeland, Barbara Maughan, Sara R. Jaffee, and Rudolf Uher. “Relative impact of maternal depression and associated risk factors on offspring psychopathology.Br J Psychiatry 200, no. 2 (February 2012): 124–29. https://doi.org/10.1192/bjp.bp.111.092346.
Barker ED, Copeland W, Maughan B, Jaffee SR, Uher R. Relative impact of maternal depression and associated risk factors on offspring psychopathology. Br J Psychiatry. 2012 Feb;200(2):124–9.
Barker, Edward D., et al. “Relative impact of maternal depression and associated risk factors on offspring psychopathology.Br J Psychiatry, vol. 200, no. 2, Feb. 2012, pp. 124–29. Pubmed, doi:10.1192/bjp.bp.111.092346.
Barker ED, Copeland W, Maughan B, Jaffee SR, Uher R. Relative impact of maternal depression and associated risk factors on offspring psychopathology. Br J Psychiatry. 2012 Feb;200(2):124–129.
Journal cover image

Published In

Br J Psychiatry

DOI

EISSN

1472-1465

Publication Date

February 2012

Volume

200

Issue

2

Start / End Page

124 / 129

Location

England

Related Subject Headings

  • Young Adult
  • Socioeconomic Factors
  • Social Support
  • Social Environment
  • Psychiatry
  • Psychiatric Status Rating Scales
  • Pregnancy
  • Mothers
  • Mother-Child Relations
  • Male