
Metoclopramide, H2 blockers, and proton pump inhibitors: pharmacotherapy for gastroesophageal reflux in neonates.
Publication
, Journal Article
Malcolm, WF; Cotten, CM
Published in: Clin Perinatol
March 2012
Pharmacotherapy for gastroesophageal reflux (GER) in neonates, aimed at interfering with this physiologic process and potentially reducing the negative sequelae that providers often attribute to GER, consists primarily of drugs that increase the viscosity of feeds, reduce stomach acidity, or improve gut motility. Medications used to treat clinical signs thought to be from GER, such as apnea, bradycardia, or feeding intolerance, are among the most commonly prescribed medications in neonatal intensive care units in the United States, despite the lack of evidence of safety and efficacy in this population.
Duke Scholars
Published In
Clin Perinatol
DOI
EISSN
1557-9840
Publication Date
March 2012
Volume
39
Issue
1
Start / End Page
99 / 109
Location
United States
Related Subject Headings
- Proton Pump Inhibitors
- Pediatrics
- Metoclopramide
- Intensive Care Units, Neonatal
- Infant, Newborn
- Humans
- Histamine H2 Antagonists
- Gastroesophageal Reflux
- Dopamine Antagonists
- 1114 Paediatrics and Reproductive Medicine
Citation
APA
Chicago
ICMJE
MLA
NLM
Malcolm, W. F., & Cotten, C. M. (2012). Metoclopramide, H2 blockers, and proton pump inhibitors: pharmacotherapy for gastroesophageal reflux in neonates. Clin Perinatol, 39(1), 99–109. https://doi.org/10.1016/j.clp.2011.12.015
Malcolm, William F., and C Michael Cotten. “Metoclopramide, H2 blockers, and proton pump inhibitors: pharmacotherapy for gastroesophageal reflux in neonates.” Clin Perinatol 39, no. 1 (March 2012): 99–109. https://doi.org/10.1016/j.clp.2011.12.015.
Malcolm WF, Cotten CM. Metoclopramide, H2 blockers, and proton pump inhibitors: pharmacotherapy for gastroesophageal reflux in neonates. Clin Perinatol. 2012 Mar;39(1):99–109.
Malcolm, William F., and C. Michael Cotten. “Metoclopramide, H2 blockers, and proton pump inhibitors: pharmacotherapy for gastroesophageal reflux in neonates.” Clin Perinatol, vol. 39, no. 1, Mar. 2012, pp. 99–109. Pubmed, doi:10.1016/j.clp.2011.12.015.
Malcolm WF, Cotten CM. Metoclopramide, H2 blockers, and proton pump inhibitors: pharmacotherapy for gastroesophageal reflux in neonates. Clin Perinatol. 2012 Mar;39(1):99–109.

Published In
Clin Perinatol
DOI
EISSN
1557-9840
Publication Date
March 2012
Volume
39
Issue
1
Start / End Page
99 / 109
Location
United States
Related Subject Headings
- Proton Pump Inhibitors
- Pediatrics
- Metoclopramide
- Intensive Care Units, Neonatal
- Infant, Newborn
- Humans
- Histamine H2 Antagonists
- Gastroesophageal Reflux
- Dopamine Antagonists
- 1114 Paediatrics and Reproductive Medicine