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A xanthine oxidase/colloidal gold enzyme electrode for amperometric biosensor applications

Publication ,  Journal Article
Zhao, J; O'Daly, JP; Henkens, RW; Stonehuerner, J; Crumbliss, AL
Published in: Biosensors and Bioelectronics
January 1, 1996

An electrode has been prepared based on xanthine oxidase adsorbed to colloidal gold and evaporated onto the surface of glassy carbon. This electrode responds to xanthine or hypoxanthine in the absence of added mediator by electrochemical oxidation of the enzymatic oxidation product, uric acid, at the electrode surface. The electrode can also be used in the presence of an electron transfer mediator to detect other substrates for xanthine oxidase such as 4-hydroxypyrimidine.

Duke Scholars

Published In

Biosensors and Bioelectronics

DOI

ISSN

0956-5663

Publication Date

January 1, 1996

Volume

11

Issue

5

Start / End Page

493 / 502

Related Subject Headings

  • Bioinformatics
  • 4018 Nanotechnology
  • 4003 Biomedical engineering
  • 3401 Analytical chemistry
  • 1007 Nanotechnology
  • 0903 Biomedical Engineering
  • 0301 Analytical Chemistry
 

Citation

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ICMJE
MLA
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Zhao, J., O’Daly, J. P., Henkens, R. W., Stonehuerner, J., & Crumbliss, A. L. (1996). A xanthine oxidase/colloidal gold enzyme electrode for amperometric biosensor applications. Biosensors and Bioelectronics, 11(5), 493–502. https://doi.org/10.1016/0956-5663(96)86786-8
Zhao, J., J. P. O’Daly, R. W. Henkens, J. Stonehuerner, and A. L. Crumbliss. “A xanthine oxidase/colloidal gold enzyme electrode for amperometric biosensor applications.” Biosensors and Bioelectronics 11, no. 5 (January 1, 1996): 493–502. https://doi.org/10.1016/0956-5663(96)86786-8.
Zhao J, O’Daly JP, Henkens RW, Stonehuerner J, Crumbliss AL. A xanthine oxidase/colloidal gold enzyme electrode for amperometric biosensor applications. Biosensors and Bioelectronics. 1996 Jan 1;11(5):493–502.
Zhao, J., et al. “A xanthine oxidase/colloidal gold enzyme electrode for amperometric biosensor applications.” Biosensors and Bioelectronics, vol. 11, no. 5, Jan. 1996, pp. 493–502. Scopus, doi:10.1016/0956-5663(96)86786-8.
Zhao J, O’Daly JP, Henkens RW, Stonehuerner J, Crumbliss AL. A xanthine oxidase/colloidal gold enzyme electrode for amperometric biosensor applications. Biosensors and Bioelectronics. 1996 Jan 1;11(5):493–502.
Journal cover image

Published In

Biosensors and Bioelectronics

DOI

ISSN

0956-5663

Publication Date

January 1, 1996

Volume

11

Issue

5

Start / End Page

493 / 502

Related Subject Headings

  • Bioinformatics
  • 4018 Nanotechnology
  • 4003 Biomedical engineering
  • 3401 Analytical chemistry
  • 1007 Nanotechnology
  • 0903 Biomedical Engineering
  • 0301 Analytical Chemistry