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Intrahepatic, extramedullary hematopoiesis mimicking hemangioma on technetium-99m red blood cell SPECT examination.

Publication ,  Journal Article
Tamm, EP; Rabushka, LS; Fishman, EK; Hruban, RH; Diehl, AM; Klein, A
Published in: Clin Imaging
1995

Cavernous hemangiomas are the most common lesion of the liver. Because of the risk of hemorrhage inherent in percutaneous biopsy of such lesions, noninterventional modalities (such as CT, ultrasound, MRI and Technetium-99m red blood cell imaging) have been utilized for differentiating them from other lesions. The sensitivities and specificities of these techniques vary greatly. Technetium-99m red blood cell imaging with planar and SPECT imaging has been shown to have an overall sensitivity of 89%, a specificity of 100%, and an overall accuracy of 92%. Despite its high accuracy, rare false positives have been reported with Technetium-99m red blood cell imaging with SPECT. Review of the literature indicates four cases of hepatocellular carcinoma, one case of hepatic angiosarcoma, and one case of hepatic metastases from colorectal carcinoma as having an appearance identical to hemangioma with this modality. We present an additional false positive of a focal region of intrahepatic extramedullary hematopoiesis in a patient with Gaucher's disease as having an appearance on Technetium-99m red blood cell imaging with SPECT identical to that of hemangioma.

Duke Scholars

Published In

Clin Imaging

DOI

ISSN

0899-7071

Publication Date

1995

Volume

19

Issue

2

Start / End Page

88 / 91

Location

United States

Related Subject Headings

  • Ultrasonography
  • Tomography, X-Ray Computed
  • Tomography, Emission-Computed, Single-Photon
  • Sodium Pertechnetate Tc 99m
  • Nuclear Medicine & Medical Imaging
  • Middle Aged
  • Magnetic Resonance Imaging
  • Liver Neoplasms
  • Liver
  • Humans
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Tamm, E. P., Rabushka, L. S., Fishman, E. K., Hruban, R. H., Diehl, A. M., & Klein, A. (1995). Intrahepatic, extramedullary hematopoiesis mimicking hemangioma on technetium-99m red blood cell SPECT examination. Clin Imaging, 19(2), 88–91. https://doi.org/10.1016/0899-7071(94)00037-d
Tamm, E. P., L. S. Rabushka, E. K. Fishman, R. H. Hruban, A. M. Diehl, and A. Klein. “Intrahepatic, extramedullary hematopoiesis mimicking hemangioma on technetium-99m red blood cell SPECT examination.Clin Imaging 19, no. 2 (1995): 88–91. https://doi.org/10.1016/0899-7071(94)00037-d.
Tamm EP, Rabushka LS, Fishman EK, Hruban RH, Diehl AM, Klein A. Intrahepatic, extramedullary hematopoiesis mimicking hemangioma on technetium-99m red blood cell SPECT examination. Clin Imaging. 1995;19(2):88–91.
Tamm, E. P., et al. “Intrahepatic, extramedullary hematopoiesis mimicking hemangioma on technetium-99m red blood cell SPECT examination.Clin Imaging, vol. 19, no. 2, 1995, pp. 88–91. Pubmed, doi:10.1016/0899-7071(94)00037-d.
Tamm EP, Rabushka LS, Fishman EK, Hruban RH, Diehl AM, Klein A. Intrahepatic, extramedullary hematopoiesis mimicking hemangioma on technetium-99m red blood cell SPECT examination. Clin Imaging. 1995;19(2):88–91.
Journal cover image

Published In

Clin Imaging

DOI

ISSN

0899-7071

Publication Date

1995

Volume

19

Issue

2

Start / End Page

88 / 91

Location

United States

Related Subject Headings

  • Ultrasonography
  • Tomography, X-Ray Computed
  • Tomography, Emission-Computed, Single-Photon
  • Sodium Pertechnetate Tc 99m
  • Nuclear Medicine & Medical Imaging
  • Middle Aged
  • Magnetic Resonance Imaging
  • Liver Neoplasms
  • Liver
  • Humans