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Design automation for DNA self-assembled nanostructures

Publication ,  Journal Article
Pistol, C; Lebeck, AR; Dwyer, C
Published in: Proceedings - Design Automation Conference
January 1, 2006

DNA self-assembly is an emerging technology with potential as a future replacement of conventional lithographic fabrication. A key challenge is the specification of appropriate DNA sequences that are optimal according to specified metrics and satisfy various design rules. To meet this challenge we developed a thermodynamics-based design automation tool to evaluate the vast DNA sequence space (2.8k base pairs) and select appropriate sequences. We use this tool to design DNA nanostructures that were previously impossible with existing text distance based tools. We also show that for nanoscale structures our approach produces superior results compared to existing tools. Copyright 2006 ACM.

Duke Scholars

Published In

Proceedings - Design Automation Conference

DOI

ISSN

0738-100X

Publication Date

January 1, 2006

Start / End Page

919 / 924
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Pistol, C., Lebeck, A. R., & Dwyer, C. (2006). Design automation for DNA self-assembled nanostructures. Proceedings - Design Automation Conference, 919–924. https://doi.org/10.1145/1146909.1147143
Pistol, C., A. R. Lebeck, and C. Dwyer. “Design automation for DNA self-assembled nanostructures.” Proceedings - Design Automation Conference, January 1, 2006, 919–24. https://doi.org/10.1145/1146909.1147143.
Pistol C, Lebeck AR, Dwyer C. Design automation for DNA self-assembled nanostructures. Proceedings - Design Automation Conference. 2006 Jan 1;919–24.
Pistol, C., et al. “Design automation for DNA self-assembled nanostructures.” Proceedings - Design Automation Conference, Jan. 2006, pp. 919–24. Scopus, doi:10.1145/1146909.1147143.
Pistol C, Lebeck AR, Dwyer C. Design automation for DNA self-assembled nanostructures. Proceedings - Design Automation Conference. 2006 Jan 1;919–924.

Published In

Proceedings - Design Automation Conference

DOI

ISSN

0738-100X

Publication Date

January 1, 2006

Start / End Page

919 / 924