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Cardiovascular genomics: estimating the total number of genes expressed in the human cardiovascular system.

Publication ,  Journal Article
Dempsey, AA; Dzau, VJ; Liew, CC
Published in: J Mol Cell Cardiol
October 2001

The number of genes encoded by the human genome has long sought to be determined. With the recent publications of the complete sequence of the human genome, the number of genes encoded by the human genome has now been estimated to be approximately 32,000-38,000. Now the next step will be to determine which of these genes are expressed in a given cell, tissue or organ. Using three unique approaches taking advantage of our current cardiovascular EST database and the complete nucleotide sequence of human chromosomes 21 and 22 as well as cDNA microarray hybridization, we estimate that between 20,930-27,160 genes are expressed in the cardiovascular system.

Duke Scholars

Published In

J Mol Cell Cardiol

DOI

ISSN

0022-2828

Publication Date

October 2001

Volume

33

Issue

10

Start / End Page

1879 / 1886

Location

England

Related Subject Headings

  • Oligonucleotide Array Sequence Analysis
  • Models, Genetic
  • Humans
  • Genome, Human
  • Expressed Sequence Tags
  • DNA, Complementary
  • Cluster Analysis
  • Chromosomes, Human, Pair 22
  • Chromosomes, Human, Pair 21
  • Cardiovascular System & Hematology
 

Citation

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Dempsey, A. A., Dzau, V. J., & Liew, C. C. (2001). Cardiovascular genomics: estimating the total number of genes expressed in the human cardiovascular system. J Mol Cell Cardiol, 33(10), 1879–1886. https://doi.org/10.1006/jmcc.2001.1447
Dempsey, A. A., V. J. Dzau, and C. C. Liew. “Cardiovascular genomics: estimating the total number of genes expressed in the human cardiovascular system.J Mol Cell Cardiol 33, no. 10 (October 2001): 1879–86. https://doi.org/10.1006/jmcc.2001.1447.
Dempsey AA, Dzau VJ, Liew CC. Cardiovascular genomics: estimating the total number of genes expressed in the human cardiovascular system. J Mol Cell Cardiol. 2001 Oct;33(10):1879–86.
Dempsey, A. A., et al. “Cardiovascular genomics: estimating the total number of genes expressed in the human cardiovascular system.J Mol Cell Cardiol, vol. 33, no. 10, Oct. 2001, pp. 1879–86. Pubmed, doi:10.1006/jmcc.2001.1447.
Dempsey AA, Dzau VJ, Liew CC. Cardiovascular genomics: estimating the total number of genes expressed in the human cardiovascular system. J Mol Cell Cardiol. 2001 Oct;33(10):1879–1886.
Journal cover image

Published In

J Mol Cell Cardiol

DOI

ISSN

0022-2828

Publication Date

October 2001

Volume

33

Issue

10

Start / End Page

1879 / 1886

Location

England

Related Subject Headings

  • Oligonucleotide Array Sequence Analysis
  • Models, Genetic
  • Humans
  • Genome, Human
  • Expressed Sequence Tags
  • DNA, Complementary
  • Cluster Analysis
  • Chromosomes, Human, Pair 22
  • Chromosomes, Human, Pair 21
  • Cardiovascular System & Hematology