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Electrowetting-based multi-microfluidics array printing of high resolution tissue construct with embedded cells and growth factors

Publication ,  Journal Article
Zhou, J; Lu, L; Byrapogu, K; Wootton, DM; Lelkes, PI; Fair, R
Published in: Virtual and Physical Prototyping
December 1, 2007

To overcome limitations of current tissue fabrication methods, explore new biocompatible materials, and develop new biomimetic manufacturing process for soft tissue, we are developing a new technology, electrowetting-based microfluidics array printing, which will be used in a solid freeform fabrication (SFF) system to meet the challenges of high resolution manufacture of hydrogel scaffolds with dimension scale less than 10 m, cell placement, growth factor delivery, and vascularization for soft tissue engineering. Preliminary work has been done on the biomaterials research, electrowetting printing, biomimetic modeling, scaffold fabrication, and system integration and control. This research is the first application of electrowetting on dielectric to tissue engineering and dispensing hydrogels.

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Published In

Virtual and Physical Prototyping

DOI

EISSN

1745-2767

ISSN

1745-2759

Publication Date

December 1, 2007

Volume

2

Issue

4

Start / End Page

217 / 223

Related Subject Headings

  • 4017 Mechanical engineering
  • 4016 Materials engineering
  • 1203 Design Practice and Management
  • 0913 Mechanical Engineering
  • 0902 Automotive Engineering
 

Citation

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ICMJE
MLA
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Zhou, J., Lu, L., Byrapogu, K., Wootton, D. M., Lelkes, P. I., & Fair, R. (2007). Electrowetting-based multi-microfluidics array printing of high resolution tissue construct with embedded cells and growth factors. Virtual and Physical Prototyping, 2(4), 217–223. https://doi.org/10.1080/17452750701747278
Zhou, J., L. Lu, K. Byrapogu, D. M. Wootton, P. I. Lelkes, and R. Fair. “Electrowetting-based multi-microfluidics array printing of high resolution tissue construct with embedded cells and growth factors.” Virtual and Physical Prototyping 2, no. 4 (December 1, 2007): 217–23. https://doi.org/10.1080/17452750701747278.
Zhou J, Lu L, Byrapogu K, Wootton DM, Lelkes PI, Fair R. Electrowetting-based multi-microfluidics array printing of high resolution tissue construct with embedded cells and growth factors. Virtual and Physical Prototyping. 2007 Dec 1;2(4):217–23.
Zhou, J., et al. “Electrowetting-based multi-microfluidics array printing of high resolution tissue construct with embedded cells and growth factors.” Virtual and Physical Prototyping, vol. 2, no. 4, Dec. 2007, pp. 217–23. Scopus, doi:10.1080/17452750701747278.
Zhou J, Lu L, Byrapogu K, Wootton DM, Lelkes PI, Fair R. Electrowetting-based multi-microfluidics array printing of high resolution tissue construct with embedded cells and growth factors. Virtual and Physical Prototyping. 2007 Dec 1;2(4):217–223.

Published In

Virtual and Physical Prototyping

DOI

EISSN

1745-2767

ISSN

1745-2759

Publication Date

December 1, 2007

Volume

2

Issue

4

Start / End Page

217 / 223

Related Subject Headings

  • 4017 Mechanical engineering
  • 4016 Materials engineering
  • 1203 Design Practice and Management
  • 0913 Mechanical Engineering
  • 0902 Automotive Engineering