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Microbiological and genotypic analysis of methicillin-resistant Staphylococcus aureus bacteremia.

Publication ,  Journal Article
McCalla, C; Smyth, DS; Robinson, DA; Steenbergen, J; Luperchio, SA; Moise, PA; Fowler, VG; Sakoulas, G
Published in: Antimicrob Agents Chemother
September 2008

In a recent landmark trial of bacteremia caused by methicillin-resistant Staphylococcus aureus (MRSA) isolates, vancomycin MICs were >or=1 microg/ml for only 16% of the isolates, and accessory gene regulator (agr) function as measured by delta-hemolysin activity was absent or reduced in only 28.1% of the isolates. This clinical study did not capture a population of MRSA isolates predictive of vancomycin treatment failure.

Duke Scholars

Published In

Antimicrob Agents Chemother

DOI

EISSN

1098-6596

Publication Date

September 2008

Volume

52

Issue

9

Start / End Page

3441 / 3443

Location

United States

Related Subject Headings

  • Vancomycin
  • Treatment Outcome
  • Staphylococcus aureus
  • Staphylococcal Infections
  • Microbiology
  • Methicillin Resistance
  • Humans
  • Hemolysin Proteins
  • Genotype
  • Endocarditis, Bacterial
 

Citation

APA
Chicago
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MLA
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McCalla, C., Smyth, D. S., Robinson, D. A., Steenbergen, J., Luperchio, S. A., Moise, P. A., … Sakoulas, G. (2008). Microbiological and genotypic analysis of methicillin-resistant Staphylococcus aureus bacteremia. Antimicrob Agents Chemother, 52(9), 3441–3443. https://doi.org/10.1128/AAC.00357-08
McCalla, Carlo, Davida S. Smyth, D Ashley Robinson, Judith Steenbergen, Steven A. Luperchio, Pamela A. Moise, Vance G. Fowler, and George Sakoulas. “Microbiological and genotypic analysis of methicillin-resistant Staphylococcus aureus bacteremia.Antimicrob Agents Chemother 52, no. 9 (September 2008): 3441–43. https://doi.org/10.1128/AAC.00357-08.
McCalla C, Smyth DS, Robinson DA, Steenbergen J, Luperchio SA, Moise PA, et al. Microbiological and genotypic analysis of methicillin-resistant Staphylococcus aureus bacteremia. Antimicrob Agents Chemother. 2008 Sep;52(9):3441–3.
McCalla, Carlo, et al. “Microbiological and genotypic analysis of methicillin-resistant Staphylococcus aureus bacteremia.Antimicrob Agents Chemother, vol. 52, no. 9, Sept. 2008, pp. 3441–43. Pubmed, doi:10.1128/AAC.00357-08.
McCalla C, Smyth DS, Robinson DA, Steenbergen J, Luperchio SA, Moise PA, Fowler VG, Sakoulas G. Microbiological and genotypic analysis of methicillin-resistant Staphylococcus aureus bacteremia. Antimicrob Agents Chemother. 2008 Sep;52(9):3441–3443.

Published In

Antimicrob Agents Chemother

DOI

EISSN

1098-6596

Publication Date

September 2008

Volume

52

Issue

9

Start / End Page

3441 / 3443

Location

United States

Related Subject Headings

  • Vancomycin
  • Treatment Outcome
  • Staphylococcus aureus
  • Staphylococcal Infections
  • Microbiology
  • Methicillin Resistance
  • Humans
  • Hemolysin Proteins
  • Genotype
  • Endocarditis, Bacterial