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Drugs for percutaneous coronary interventions.

Publication ,  Journal Article
Published in: Med Lett Drugs Ther
December 6, 2004

Many combinations of anticoagulants and antiplatelet drugs have been used to treat patients undergoing a percutaneous coronary intervention (PCI). Among anticoagulants, enoxaparin has some theoretical advantages over unfractionated heparin, but in clinical trials no advantage in outcome has been demonstrated in PCI. Bivalirudin, a direct thrombin inhibitor, has been associated with a lower risk of bleeding than unfractionated heparin. Among antiplatelet drugs, use of clopidogrel plus aspirin has led to a reduction in cardiovascular events; all patients undergoing PCI should receive both. Addition of a GP IIb/IIIa inhibitor may lower mortality rates further, particularly in high-risk patients such as diabetics.

Duke Scholars

Published In

Med Lett Drugs Ther

ISSN

0025-732X

Publication Date

December 6, 2004

Volume

47

Issue

1197-1198

Start / End Page

100 / 102

Location

United States

Related Subject Headings

  • Thrombosis
  • Platelet Glycoprotein GPIIb-IIIa Complex
  • Platelet Aggregation Inhibitors
  • Pharmacology & Pharmacy
  • Male
  • Humans
  • Female
  • Clinical Trials as Topic
  • Anticoagulants
  • Angioplasty, Balloon, Coronary
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Drugs for percutaneous coronary interventions. (2004). Med Lett Drugs Ther, 47(1197–1198), 100–102.
Drugs for percutaneous coronary interventions.Med Lett Drugs Ther 47, no. 1197–1198 (December 6, 2004): 100–102.
Drugs for percutaneous coronary interventions. Med Lett Drugs Ther. 2004 Dec 6;47(1197–1198):100–2.
Drugs for percutaneous coronary interventions.Med Lett Drugs Ther, vol. 47, no. 1197–1198, Dec. 2004, pp. 100–02.
Drugs for percutaneous coronary interventions. Med Lett Drugs Ther. 2004 Dec 6;47(1197–1198):100–102.

Published In

Med Lett Drugs Ther

ISSN

0025-732X

Publication Date

December 6, 2004

Volume

47

Issue

1197-1198

Start / End Page

100 / 102

Location

United States

Related Subject Headings

  • Thrombosis
  • Platelet Glycoprotein GPIIb-IIIa Complex
  • Platelet Aggregation Inhibitors
  • Pharmacology & Pharmacy
  • Male
  • Humans
  • Female
  • Clinical Trials as Topic
  • Anticoagulants
  • Angioplasty, Balloon, Coronary