Drugs for percutaneous coronary interventions.
Publication
, Journal Article
Published in: Med Lett Drugs Ther
December 6, 2004
Many combinations of anticoagulants and antiplatelet drugs have been used to treat patients undergoing a percutaneous coronary intervention (PCI). Among anticoagulants, enoxaparin has some theoretical advantages over unfractionated heparin, but in clinical trials no advantage in outcome has been demonstrated in PCI. Bivalirudin, a direct thrombin inhibitor, has been associated with a lower risk of bleeding than unfractionated heparin. Among antiplatelet drugs, use of clopidogrel plus aspirin has led to a reduction in cardiovascular events; all patients undergoing PCI should receive both. Addition of a GP IIb/IIIa inhibitor may lower mortality rates further, particularly in high-risk patients such as diabetics.
Duke Scholars
Published In
Med Lett Drugs Ther
ISSN
0025-732X
Publication Date
December 6, 2004
Volume
47
Issue
1197-1198
Start / End Page
100 / 102
Location
United States
Related Subject Headings
- Thrombosis
- Platelet Glycoprotein GPIIb-IIIa Complex
- Platelet Aggregation Inhibitors
- Pharmacology & Pharmacy
- Male
- Humans
- Female
- Clinical Trials as Topic
- Anticoagulants
- Angioplasty, Balloon, Coronary
Citation
APA
Chicago
ICMJE
MLA
NLM
Drugs for percutaneous coronary interventions. (2004). Med Lett Drugs Ther, 47(1197–1198), 100–102.
“Drugs for percutaneous coronary interventions.” Med Lett Drugs Ther 47, no. 1197–1198 (December 6, 2004): 100–102.
Drugs for percutaneous coronary interventions. Med Lett Drugs Ther. 2004 Dec 6;47(1197–1198):100–2.
“Drugs for percutaneous coronary interventions.” Med Lett Drugs Ther, vol. 47, no. 1197–1198, Dec. 2004, pp. 100–02.
Drugs for percutaneous coronary interventions. Med Lett Drugs Ther. 2004 Dec 6;47(1197–1198):100–102.
Published In
Med Lett Drugs Ther
ISSN
0025-732X
Publication Date
December 6, 2004
Volume
47
Issue
1197-1198
Start / End Page
100 / 102
Location
United States
Related Subject Headings
- Thrombosis
- Platelet Glycoprotein GPIIb-IIIa Complex
- Platelet Aggregation Inhibitors
- Pharmacology & Pharmacy
- Male
- Humans
- Female
- Clinical Trials as Topic
- Anticoagulants
- Angioplasty, Balloon, Coronary