Skip to main content
Journal cover image

The oral microbiome in health and disease and the potential impact on personalized dental medicine.

Publication ,  Journal Article
Zarco, MF; Vess, TJ; Ginsburg, GS
Published in: Oral Dis
March 2012

Every human body contains a personalized microbiome that is essential to maintaining health but capable of eliciting disease. The oral microbiome is particularly imperative to health because it can cause both oral and systemic disease. The oral microbiome rests within biofilms throughout the oral cavity, forming an ecosystem that maintains health when in equilibrium. However, certain ecological shifts in the microbiome allow pathogens to manifest and cause disease. Severe forms of oral disease may result in systemic disease at different body sites. Microbiomics and metagenomics are two fields of research that have emerged to identify the presence of specific microbes in the body and understand the nature of the microbiome activity during both health and disease. The analysis of the microbiome and its genomes will pave the way for more effective therapeutic and diagnostic techniques and, ultimately, contribute to the development of personalized medicine and personalized dental medicine.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

Oral Dis

DOI

EISSN

1601-0825

Publication Date

March 2012

Volume

18

Issue

2

Start / End Page

109 / 120

Location

Denmark

Related Subject Headings

  • Saliva
  • Probiotics
  • Precision Medicine
  • Prebiotics
  • Periodontitis
  • Mouth Neoplasms
  • Mouth
  • Metagenomics
  • Metagenome
  • Humans
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Zarco, M. F., Vess, T. J., & Ginsburg, G. S. (2012). The oral microbiome in health and disease and the potential impact on personalized dental medicine. Oral Dis, 18(2), 109–120. https://doi.org/10.1111/j.1601-0825.2011.01851.x
Zarco, M. F., T. J. Vess, and G. S. Ginsburg. “The oral microbiome in health and disease and the potential impact on personalized dental medicine.Oral Dis 18, no. 2 (March 2012): 109–20. https://doi.org/10.1111/j.1601-0825.2011.01851.x.
Zarco MF, Vess TJ, Ginsburg GS. The oral microbiome in health and disease and the potential impact on personalized dental medicine. Oral Dis. 2012 Mar;18(2):109–20.
Zarco, M. F., et al. “The oral microbiome in health and disease and the potential impact on personalized dental medicine.Oral Dis, vol. 18, no. 2, Mar. 2012, pp. 109–20. Pubmed, doi:10.1111/j.1601-0825.2011.01851.x.
Zarco MF, Vess TJ, Ginsburg GS. The oral microbiome in health and disease and the potential impact on personalized dental medicine. Oral Dis. 2012 Mar;18(2):109–120.
Journal cover image

Published In

Oral Dis

DOI

EISSN

1601-0825

Publication Date

March 2012

Volume

18

Issue

2

Start / End Page

109 / 120

Location

Denmark

Related Subject Headings

  • Saliva
  • Probiotics
  • Precision Medicine
  • Prebiotics
  • Periodontitis
  • Mouth Neoplasms
  • Mouth
  • Metagenomics
  • Metagenome
  • Humans