Understanding the physiology of the blood-brain barrier: In vitro models
Publication
, Journal Article
Grant, GA; Abbott, NJ; Janigro, D
Published in: News in Physiological Sciences
January 1, 1998
Endothelial cells exposed to inductive central nervous system factors differentiate into a blood-brain barrier phenotype. The blood-brain barrier frequently obstructs the passage of chemotherapeutics into the brain. Tissue culture systems have been developed to reproduce key properties of the intact blood-brain barrier and to allow for testing of mechanisms of transendothelial drug permeation.
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Published In
News in Physiological Sciences
DOI
ISSN
0886-1714
Publication Date
January 1, 1998
Volume
13
Issue
6
Start / End Page
287 / 293
Related Subject Headings
- Physiology
- Biochemistry & Molecular Biology
- 3208 Medical physiology
- 1116 Medical Physiology
- 1106 Human Movement and Sports Sciences
- 0606 Physiology
Citation
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Grant, G. A., Abbott, N. J., & Janigro, D. (1998). Understanding the physiology of the blood-brain barrier: In vitro models. News in Physiological Sciences, 13(6), 287–293. https://doi.org/10.1152/physiologyonline.1998.13.6.287
Grant, G. A., N. J. Abbott, and D. Janigro. “Understanding the physiology of the blood-brain barrier: In vitro models.” News in Physiological Sciences 13, no. 6 (January 1, 1998): 287–93. https://doi.org/10.1152/physiologyonline.1998.13.6.287.
Grant GA, Abbott NJ, Janigro D. Understanding the physiology of the blood-brain barrier: In vitro models. News in Physiological Sciences. 1998 Jan 1;13(6):287–93.
Grant, G. A., et al. “Understanding the physiology of the blood-brain barrier: In vitro models.” News in Physiological Sciences, vol. 13, no. 6, Jan. 1998, pp. 287–93. Scopus, doi:10.1152/physiologyonline.1998.13.6.287.
Grant GA, Abbott NJ, Janigro D. Understanding the physiology of the blood-brain barrier: In vitro models. News in Physiological Sciences. 1998 Jan 1;13(6):287–293.
Published In
News in Physiological Sciences
DOI
ISSN
0886-1714
Publication Date
January 1, 1998
Volume
13
Issue
6
Start / End Page
287 / 293
Related Subject Headings
- Physiology
- Biochemistry & Molecular Biology
- 3208 Medical physiology
- 1116 Medical Physiology
- 1106 Human Movement and Sports Sciences
- 0606 Physiology