A new method for the synthesis of 1,4,5-oxadiazocines and its application in the structure modification of natural products
Publication
, Journal Article
Liu, W; Guan, Z; Singh, SB
Published in: Tetrahedron Letters
November 14, 2005
A new method for the synthesis of eight-membered heterocyclic 1,4,5-oxadiazocines has been described from β-diketone and β,β,β-triketone with an acidic α-hydrogen. The method entails the reaction of a di- or triketone with 2-hydroxyethylhydrazine and an aldehyde in the presence of acetic acid providing respectable yield. © 2005 Elsevier Ltd. All rights reserved.
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Published In
Tetrahedron Letters
DOI
ISSN
0040-4039
Publication Date
November 14, 2005
Volume
46
Issue
46
Start / End Page
8009 / 8012
Related Subject Headings
- Organic Chemistry
- 3405 Organic chemistry
- 3404 Medicinal and biomolecular chemistry
- 3101 Biochemistry and cell biology
- 0305 Organic Chemistry
- 0304 Medicinal and Biomolecular Chemistry
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Liu, W., Guan, Z., & Singh, S. B. (2005). A new method for the synthesis of 1,4,5-oxadiazocines and its application in the structure modification of natural products. Tetrahedron Letters, 46(46), 8009–8012. https://doi.org/10.1016/j.tetlet.2005.09.069
Liu, W., Z. Guan, and S. B. Singh. “A new method for the synthesis of 1,4,5-oxadiazocines and its application in the structure modification of natural products.” Tetrahedron Letters 46, no. 46 (November 14, 2005): 8009–12. https://doi.org/10.1016/j.tetlet.2005.09.069.
Liu W, Guan Z, Singh SB. A new method for the synthesis of 1,4,5-oxadiazocines and its application in the structure modification of natural products. Tetrahedron Letters. 2005 Nov 14;46(46):8009–12.
Liu, W., et al. “A new method for the synthesis of 1,4,5-oxadiazocines and its application in the structure modification of natural products.” Tetrahedron Letters, vol. 46, no. 46, Nov. 2005, pp. 8009–12. Scopus, doi:10.1016/j.tetlet.2005.09.069.
Liu W, Guan Z, Singh SB. A new method for the synthesis of 1,4,5-oxadiazocines and its application in the structure modification of natural products. Tetrahedron Letters. 2005 Nov 14;46(46):8009–8012.
Published In
Tetrahedron Letters
DOI
ISSN
0040-4039
Publication Date
November 14, 2005
Volume
46
Issue
46
Start / End Page
8009 / 8012
Related Subject Headings
- Organic Chemistry
- 3405 Organic chemistry
- 3404 Medicinal and biomolecular chemistry
- 3101 Biochemistry and cell biology
- 0305 Organic Chemistry
- 0304 Medicinal and Biomolecular Chemistry