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Localization and characterization of peptide acylation with Ester linkage by electron capture dissociation FTICR/MS

Publication ,  Journal Article
Guan, Z; Griffin, PR
Published in: Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics
December 1, 2002

The localization and characterization of peptide acylation with ester linkage by electron capture dissociation FTICR/MS were discussed. The electron capture dissociation (ECD) FTICR/MS were applied to ghrelin, a 28-residue acylated growth-hormone-releasing peptide. It was found that the precursor molecular ions isolated by stored-waveform inverse Fourier transform (SWIFT) ejection were irradiated with low energy electrons from the heated EI filament. The structure of the attached acyl group was also deduced from the accurate mass measurement of the fatty acid neutral loss from the molecular ion.

Duke Scholars

Published In

Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics

Publication Date

December 1, 2002

Start / End Page

857 / 858
 

Citation

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Guan, Z., & Griffin, P. R. (2002). Localization and characterization of peptide acylation with Ester linkage by electron capture dissociation FTICR/MS. Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics, 857–858.
Guan, Z., and P. R. Griffin. “Localization and characterization of peptide acylation with Ester linkage by electron capture dissociation FTICR/MS.” Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics, December 1, 2002, 857–58.
Guan Z, Griffin PR. Localization and characterization of peptide acylation with Ester linkage by electron capture dissociation FTICR/MS. Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics. 2002 Dec 1;857–8.
Guan, Z., and P. R. Griffin. “Localization and characterization of peptide acylation with Ester linkage by electron capture dissociation FTICR/MS.” Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics, Dec. 2002, pp. 857–58.
Guan Z, Griffin PR. Localization and characterization of peptide acylation with Ester linkage by electron capture dissociation FTICR/MS. Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics. 2002 Dec 1;857–858.

Published In

Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics

Publication Date

December 1, 2002

Start / End Page

857 / 858