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Tests for 2 × 2 tables in clinical trials

Publication ,  Journal Article
Hasselblad, V; Lokhnygina, Y
Published in: Journal of Modern Applied Statistical Methods
January 1, 2007

Five standard tests are compared: chi-squared, Fisher's exact, Yates' correction, Fisher's exact mid-p, and Barnard's. Yates' is always inferior to Fisher's exact. Fisher's exact is so conservative that one should look for alternatives. For certain sample sizes, Fisher's mid-p or Barnard's test maintain the nominal alpha and have superior power. Copyright © 2007 JMASM, Inc.

Duke Scholars

Published In

Journal of Modern Applied Statistical Methods

DOI

EISSN

1538-9472

ISSN

1538-9472

Publication Date

January 1, 2007

Volume

6

Issue

2

Start / End Page

456 / 468

Related Subject Headings

  • Statistics & Probability
  • 4905 Statistics
  • 0104 Statistics
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Hasselblad, V., & Lokhnygina, Y. (2007). Tests for 2 × 2 tables in clinical trials. Journal of Modern Applied Statistical Methods, 6(2), 456–468. https://doi.org/10.22237/jmasm/1193890140
Hasselblad, V., and Y. Lokhnygina. “Tests for 2 × 2 tables in clinical trials.” Journal of Modern Applied Statistical Methods 6, no. 2 (January 1, 2007): 456–68. https://doi.org/10.22237/jmasm/1193890140.
Hasselblad V, Lokhnygina Y. Tests for 2 × 2 tables in clinical trials. Journal of Modern Applied Statistical Methods. 2007 Jan 1;6(2):456–68.
Hasselblad, V., and Y. Lokhnygina. “Tests for 2 × 2 tables in clinical trials.” Journal of Modern Applied Statistical Methods, vol. 6, no. 2, Jan. 2007, pp. 456–68. Scopus, doi:10.22237/jmasm/1193890140.
Hasselblad V, Lokhnygina Y. Tests for 2 × 2 tables in clinical trials. Journal of Modern Applied Statistical Methods. 2007 Jan 1;6(2):456–468.

Published In

Journal of Modern Applied Statistical Methods

DOI

EISSN

1538-9472

ISSN

1538-9472

Publication Date

January 1, 2007

Volume

6

Issue

2

Start / End Page

456 / 468

Related Subject Headings

  • Statistics & Probability
  • 4905 Statistics
  • 0104 Statistics