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Old enzymes, new tricks: sirtuins are NAD(+)-dependent de-acylases.

Publication ,  Journal Article
Hirschey, MD
Published in: Cell Metab
December 7, 2011

Seven mammalian sirtuins are nicotinamide adenine dinucleotide (NAD)(+)-dependent deacetylases and are important modulators of energy metabolism and stress resistance. Two new studies by Du et al. (2011) and Peng et al. (2011) identify a new enzymatic activity for SIRT5, expanding the cellular repertoire of posttranslational modifications targeted by the sirtuins.

Duke Scholars

Published In

Cell Metab

DOI

EISSN

1932-7420

Publication Date

December 7, 2011

Volume

14

Issue

6

Start / End Page

718 / 719

Location

United States

Related Subject Headings

  • Endocrinology & Metabolism
  • 3205 Medical biochemistry and metabolomics
  • 3101 Biochemistry and cell biology
  • 1101 Medical Biochemistry and Metabolomics
  • 0601 Biochemistry and Cell Biology
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Hirschey, M. D. (2011). Old enzymes, new tricks: sirtuins are NAD(+)-dependent de-acylases. Cell Metab, 14(6), 718–719. https://doi.org/10.1016/j.cmet.2011.10.006
Hirschey, Matthew D. “Old enzymes, new tricks: sirtuins are NAD(+)-dependent de-acylases.Cell Metab 14, no. 6 (December 7, 2011): 718–19. https://doi.org/10.1016/j.cmet.2011.10.006.
Hirschey MD. Old enzymes, new tricks: sirtuins are NAD(+)-dependent de-acylases. Cell Metab. 2011 Dec 7;14(6):718–9.
Hirschey, Matthew D. “Old enzymes, new tricks: sirtuins are NAD(+)-dependent de-acylases.Cell Metab, vol. 14, no. 6, Dec. 2011, pp. 718–19. Pubmed, doi:10.1016/j.cmet.2011.10.006.
Hirschey MD. Old enzymes, new tricks: sirtuins are NAD(+)-dependent de-acylases. Cell Metab. 2011 Dec 7;14(6):718–719.
Journal cover image

Published In

Cell Metab

DOI

EISSN

1932-7420

Publication Date

December 7, 2011

Volume

14

Issue

6

Start / End Page

718 / 719

Location

United States

Related Subject Headings

  • Endocrinology & Metabolism
  • 3205 Medical biochemistry and metabolomics
  • 3101 Biochemistry and cell biology
  • 1101 Medical Biochemistry and Metabolomics
  • 0601 Biochemistry and Cell Biology