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Comparison of the expression of three highly related genes, Fgf8, Fgf17 and Fgf18, in the mouse embryo.

Publication ,  Journal Article
Maruoka, Y; Ohbayashi, N; Hoshikawa, M; Itoh, N; Hogan, BL; Furuta, Y
Published in: Mech Dev
June 1998

In mammals, 16 members of the Fgf family have so far been described with diverse roles in embryonic cell growth and differentiation. Here, we report the expression from early streak stage to midgestation of two newly-identified murine genes, Fgf17 and Fgf18, that are most closely related to Fgf8 (63.7% and 56.8% identical, respectively, at the amino acid level). Fgf17 is expressed during gastrulation but at lower levels than Fgf8, while Fgf18 RNA is not expressed until later, in paraxial mesoderm. In the developing tail bud, each Fgf gene shows a different pattern of transcription. Distinct and overlapping expression patterns are also described in the developing brain and limbs.

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Published In

Mech Dev

DOI

ISSN

0925-4773

Publication Date

June 1998

Volume

74

Issue

1-2

Start / End Page

175 / 177

Location

Ireland

Related Subject Headings

  • Transcription, Genetic
  • Nerve Tissue Proteins
  • Mice, Inbred ICR
  • Mice
  • Mesoderm
  • Gestational Age
  • Gene Expression Regulation, Developmental
  • Fibroblast Growth Factors
  • Fibroblast Growth Factor 8
  • Fetal Proteins
 

Citation

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Maruoka, Y., Ohbayashi, N., Hoshikawa, M., Itoh, N., Hogan, B. L., & Furuta, Y. (1998). Comparison of the expression of three highly related genes, Fgf8, Fgf17 and Fgf18, in the mouse embryo. Mech Dev, 74(1–2), 175–177. https://doi.org/10.1016/s0925-4773(98)00061-6
Maruoka, Y., N. Ohbayashi, M. Hoshikawa, N. Itoh, B. L. Hogan, and Y. Furuta. “Comparison of the expression of three highly related genes, Fgf8, Fgf17 and Fgf18, in the mouse embryo.Mech Dev 74, no. 1–2 (June 1998): 175–77. https://doi.org/10.1016/s0925-4773(98)00061-6.
Maruoka Y, Ohbayashi N, Hoshikawa M, Itoh N, Hogan BL, Furuta Y. Comparison of the expression of three highly related genes, Fgf8, Fgf17 and Fgf18, in the mouse embryo. Mech Dev. 1998 Jun;74(1–2):175–7.
Maruoka, Y., et al. “Comparison of the expression of three highly related genes, Fgf8, Fgf17 and Fgf18, in the mouse embryo.Mech Dev, vol. 74, no. 1–2, June 1998, pp. 175–77. Pubmed, doi:10.1016/s0925-4773(98)00061-6.
Maruoka Y, Ohbayashi N, Hoshikawa M, Itoh N, Hogan BL, Furuta Y. Comparison of the expression of three highly related genes, Fgf8, Fgf17 and Fgf18, in the mouse embryo. Mech Dev. 1998 Jun;74(1–2):175–177.
Journal cover image

Published In

Mech Dev

DOI

ISSN

0925-4773

Publication Date

June 1998

Volume

74

Issue

1-2

Start / End Page

175 / 177

Location

Ireland

Related Subject Headings

  • Transcription, Genetic
  • Nerve Tissue Proteins
  • Mice, Inbred ICR
  • Mice
  • Mesoderm
  • Gestational Age
  • Gene Expression Regulation, Developmental
  • Fibroblast Growth Factors
  • Fibroblast Growth Factor 8
  • Fetal Proteins