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The effect of protein synthesis inhibition on the entry of messenger RNA into the cytoplasm of sea urchin embryos.

Publication ,  Journal Article
Hogan, B; Gross, PR
Published in: J Cell Biol
June 1971

Emetine is a potent inhibitor of protein synthesis in sea urchin embryos. At a concentration of the drug that rapidly inhibits protein synthesis in blastulae by 95%, uridine incorporation into RNA continues for more than 1 hr and presumptive histone messenger RNA is synthesized and transported into the cytoplasm where it is apparently associated with polyribosomes. Possible explanations of this result and its implications for the "informasome" theory of messenger transport in embryonic cells are discussed.

Duke Scholars

Published In

J Cell Biol

DOI

ISSN

0021-9525

Publication Date

June 1971

Volume

49

Issue

3

Start / End Page

692 / 701

Location

United States

Related Subject Headings

  • Uridine
  • Tritium
  • Ribosomes
  • RNA, Ribosomal
  • RNA, Messenger
  • RNA
  • Proteins
  • Protein Biosynthesis
  • Morphogenesis
  • Histones
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Hogan, B., & Gross, P. R. (1971). The effect of protein synthesis inhibition on the entry of messenger RNA into the cytoplasm of sea urchin embryos. J Cell Biol, 49(3), 692–701. https://doi.org/10.1083/jcb.49.3.692
Hogan, B., and P. R. Gross. “The effect of protein synthesis inhibition on the entry of messenger RNA into the cytoplasm of sea urchin embryos.J Cell Biol 49, no. 3 (June 1971): 692–701. https://doi.org/10.1083/jcb.49.3.692.
Hogan, B., and P. R. Gross. “The effect of protein synthesis inhibition on the entry of messenger RNA into the cytoplasm of sea urchin embryos.J Cell Biol, vol. 49, no. 3, June 1971, pp. 692–701. Pubmed, doi:10.1083/jcb.49.3.692.

Published In

J Cell Biol

DOI

ISSN

0021-9525

Publication Date

June 1971

Volume

49

Issue

3

Start / End Page

692 / 701

Location

United States

Related Subject Headings

  • Uridine
  • Tritium
  • Ribosomes
  • RNA, Ribosomal
  • RNA, Messenger
  • RNA
  • Proteins
  • Protein Biosynthesis
  • Morphogenesis
  • Histones