Bayesian analysis of paired survival data using a bivariate exponential distribution.

We consider a Bayesian analysis method of paired survival data using a bivariate exponential model proposed by Moran (1967, Biometrika 54:385-394). Important features of Moran's model include that the marginal distributions are exponential and the range of the correlation coefficient is between 0 and 1. These contrast with the popular exponential model with gamma frailty. Despite these nice properties, statistical analysis with Moran's model has been hampered by lack of a closed form likelihood function. In this paper, we introduce a latent variable to circumvent the difficulty in the Bayesian computation. We also consider a model checking procedure using the predictive Bayesian P-value.

Duke Scholars

Author Sin-Ho Jung Biostatistics & Bioinformatics, Division of Integrative Geno ...