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D-amphetamine challenge effects on Wisconsin Card Sort Test. Performance in schizotypal personality disorder.

Publication ,  Journal Article
Siegel, BV; Trestman, RL; O'Flaithbheartaigh, S; Mitropoulou, V; Amin, F; Kirrane, R; Silverman, J; Schmeidler, J; Keefe, RS; Siever, LJ
Published in: Schizophr Res
May 1996

The authors assessed the effects on Wisconsin Card Sort (WCST) performance and psychiatric symptoms of 30 mg d-amphetamine, a dopamine and norepinephrine agonist, vs placebo in nine patients with schizotypal personality disorder (SPD). Patients, particularly those who made more perseverative errors, demonstrated amphetamine-associated improvement on WCST performance. The data in this preliminary study suggest that some of the cognitive dysfunction present in SPD may improve with amphetamine challenge.

Duke Scholars

Published In

Schizophr Res

DOI

ISSN

0920-9964

Publication Date

May 1996

Volume

20

Issue

1-2

Start / End Page

29 / 32

Location

Netherlands

Related Subject Headings

  • Schizotypal Personality Disorder
  • Schizophrenia
  • Psychiatry
  • Problem Solving
  • Norepinephrine
  • Neuropsychological Tests
  • Middle Aged
  • Male
  • Humans
  • Female
 

Citation

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Siegel, B. V., Trestman, R. L., O’Flaithbheartaigh, S., Mitropoulou, V., Amin, F., Kirrane, R., … Siever, L. J. (1996). D-amphetamine challenge effects on Wisconsin Card Sort Test. Performance in schizotypal personality disorder. Schizophr Res, 20(1–2), 29–32. https://doi.org/10.1016/0920-9964(95)00002-x
Siegel, B. V., R. L. Trestman, S. O’Flaithbheartaigh, V. Mitropoulou, F. Amin, R. Kirrane, J. Silverman, J. Schmeidler, R. S. Keefe, and L. J. Siever. “D-amphetamine challenge effects on Wisconsin Card Sort Test. Performance in schizotypal personality disorder.Schizophr Res 20, no. 1–2 (May 1996): 29–32. https://doi.org/10.1016/0920-9964(95)00002-x.
Siegel BV, Trestman RL, O’Flaithbheartaigh S, Mitropoulou V, Amin F, Kirrane R, et al. D-amphetamine challenge effects on Wisconsin Card Sort Test. Performance in schizotypal personality disorder. Schizophr Res. 1996 May;20(1–2):29–32.
Siegel, B. V., et al. “D-amphetamine challenge effects on Wisconsin Card Sort Test. Performance in schizotypal personality disorder.Schizophr Res, vol. 20, no. 1–2, May 1996, pp. 29–32. Pubmed, doi:10.1016/0920-9964(95)00002-x.
Siegel BV, Trestman RL, O’Flaithbheartaigh S, Mitropoulou V, Amin F, Kirrane R, Silverman J, Schmeidler J, Keefe RS, Siever LJ. D-amphetamine challenge effects on Wisconsin Card Sort Test. Performance in schizotypal personality disorder. Schizophr Res. 1996 May;20(1–2):29–32.
Journal cover image

Published In

Schizophr Res

DOI

ISSN

0920-9964

Publication Date

May 1996

Volume

20

Issue

1-2

Start / End Page

29 / 32

Location

Netherlands

Related Subject Headings

  • Schizotypal Personality Disorder
  • Schizophrenia
  • Psychiatry
  • Problem Solving
  • Norepinephrine
  • Neuropsychological Tests
  • Middle Aged
  • Male
  • Humans
  • Female