Metabolites at a biomaterial-tissue interface sampled by microdialysis - a comparison of the subcutaneous foreign body response in humans and rats over 8 days
Publication
, Other
Wisniewski, N; Rajamand, N; Reichert, W; Klitzman, B; Ungerstedt, U
Published in: Annals of Biomedical Engineering
December 1, 2000
The purpose of this work was to study how closely the rat models the human subcutaneous (SQ) foreign body response. Polyamide microdialysis probes (CMA/Microdialysis; Solna, Sweden) were implanted subcutaneously in healthy human volunteers and in Sprague Dawley rats (n = 12 probes per group). Microdialysis samples were collected over 8 days and analyzed for glucose, lactate, pyruvate and glycerol content. Correpsonding blood samples were analyzed. Results showed significant differences in the microdialysate concentrations and 8 day trends in humans in rats.
Duke Scholars
Published In
Annals of Biomedical Engineering
ISSN
0090-6964
Publication Date
December 1, 2000
Volume
28
Issue
SUPPL. 1
Related Subject Headings
- Biomedical Engineering
- 11 Medical and Health Sciences
- 09 Engineering
Citation
APA
Chicago
ICMJE
MLA
NLM
Wisniewski, N., Rajamand, N., Reichert, W., Klitzman, B., & Ungerstedt, U. (2000). Metabolites at a biomaterial-tissue interface sampled by microdialysis - a comparison of the subcutaneous foreign body response in humans and rats over 8 days. Annals of Biomedical Engineering.
Wisniewski, N., N. Rajamand, W. Reichert, B. Klitzman, and U. Ungerstedt. “Metabolites at a biomaterial-tissue interface sampled by microdialysis - a comparison of the subcutaneous foreign body response in humans and rats over 8 days.” Annals of Biomedical Engineering, December 1, 2000.
Wisniewski N, Rajamand N, Reichert W, Klitzman B, Ungerstedt U. Metabolites at a biomaterial-tissue interface sampled by microdialysis - a comparison of the subcutaneous foreign body response in humans and rats over 8 days. Vol. 28, Annals of Biomedical Engineering. 2000.
Wisniewski, N., et al. “Metabolites at a biomaterial-tissue interface sampled by microdialysis - a comparison of the subcutaneous foreign body response in humans and rats over 8 days.” Annals of Biomedical Engineering, vol. 28, no. SUPPL. 1, 1 Dec. 2000.
Wisniewski N, Rajamand N, Reichert W, Klitzman B, Ungerstedt U. Metabolites at a biomaterial-tissue interface sampled by microdialysis - a comparison of the subcutaneous foreign body response in humans and rats over 8 days. Annals of Biomedical Engineering. 2000.
Published In
Annals of Biomedical Engineering
ISSN
0090-6964
Publication Date
December 1, 2000
Volume
28
Issue
SUPPL. 1
Related Subject Headings
- Biomedical Engineering
- 11 Medical and Health Sciences
- 09 Engineering