Can prenylcysteines be exploited as ligands for mammalian multidrug-resistance transporters?
Publication
, Journal Article
Hurwitz, LM; Casey, PJ
Published in: Chem Biol
October 1997
The overexpression of specific transport proteins in the membrane of many cancer cells renders these cells resistant to many therapeutic drugs. Some lipid-modified cysteine compounds inhibit one drug-transporting protein, indicating the potential of developing such compounds as therapeutic agents.
Duke Scholars
Altmetric Attention Stats
Dimensions Citation Stats
Published In
Chem Biol
DOI
ISSN
1074-5521
Publication Date
October 1997
Volume
4
Issue
10
Start / End Page
711 / 715
Location
United States
Related Subject Headings
- Protein Prenylation
- Organic Chemistry
- Ligands
- Humans
- Drug Resistance, Multiple
- Cysteine
- Animals
- ATP-Binding Cassette Transporters
- 3404 Medicinal and biomolecular chemistry
- 3101 Biochemistry and cell biology
Citation
APA
Chicago
ICMJE
MLA
NLM
Hurwitz, L. M., & Casey, P. J. (1997). Can prenylcysteines be exploited as ligands for mammalian multidrug-resistance transporters? Chem Biol, 4(10), 711–715. https://doi.org/10.1016/s1074-5521(97)90308-2
Hurwitz, L. M., and P. J. Casey. “Can prenylcysteines be exploited as ligands for mammalian multidrug-resistance transporters?” Chem Biol 4, no. 10 (October 1997): 711–15. https://doi.org/10.1016/s1074-5521(97)90308-2.
Hurwitz LM, Casey PJ. Can prenylcysteines be exploited as ligands for mammalian multidrug-resistance transporters? Chem Biol. 1997 Oct;4(10):711–5.
Hurwitz, L. M., and P. J. Casey. “Can prenylcysteines be exploited as ligands for mammalian multidrug-resistance transporters?” Chem Biol, vol. 4, no. 10, Oct. 1997, pp. 711–15. Pubmed, doi:10.1016/s1074-5521(97)90308-2.
Hurwitz LM, Casey PJ. Can prenylcysteines be exploited as ligands for mammalian multidrug-resistance transporters? Chem Biol. 1997 Oct;4(10):711–715.
Published In
Chem Biol
DOI
ISSN
1074-5521
Publication Date
October 1997
Volume
4
Issue
10
Start / End Page
711 / 715
Location
United States
Related Subject Headings
- Protein Prenylation
- Organic Chemistry
- Ligands
- Humans
- Drug Resistance, Multiple
- Cysteine
- Animals
- ATP-Binding Cassette Transporters
- 3404 Medicinal and biomolecular chemistry
- 3101 Biochemistry and cell biology