Intracerebral hemorrhage outcome: apolipoprotein E genotype, hematoma, and edema volumes.
Publication
, Journal Article
McCarron, MO; Hoffmann, KL; DeLong, DM; Gray, L; Saunders, AM; Alberts, MJ
Published in: Neurology
December 10, 1999
We investigated whether early hematoma or edema volumes could explain the adverse association between APOE epsilon4 and survival in intracerebral hemorrhage. Among 102 patients, epsilon4 carriers had a higher mortality rate than non-epsilon4 carriers (38 versus 24%, p = 0.05). Nonsurvivors had larger hematoma (75.5 cm3 versus 27.1 cm3, p<0.001) and edema volumes (37.5 cm3 versus 17.1 cm3, p<0.01), but these were not associated with epsilon4 after adjusting for race, age, and type of hemorrhage.
Duke Scholars
Published In
Neurology
DOI
ISSN
0028-3878
Publication Date
December 10, 1999
Volume
53
Issue
9
Start / End Page
2176 / 2179
Location
United States
Related Subject Headings
- Survival Rate
- Prognosis
- Neurology & Neurosurgery
- Middle Aged
- Male
- Humans
- Hematoma
- Genotype
- Genetic Carrier Screening
- Gene Frequency
Citation
APA
Chicago
ICMJE
MLA
NLM
McCarron, M. O., Hoffmann, K. L., DeLong, D. M., Gray, L., Saunders, A. M., & Alberts, M. J. (1999). Intracerebral hemorrhage outcome: apolipoprotein E genotype, hematoma, and edema volumes. Neurology, 53(9), 2176–2179. https://doi.org/10.1212/wnl.53.9.2176
McCarron, M. O., K. L. Hoffmann, D. M. DeLong, L. Gray, A. M. Saunders, and M. J. Alberts. “Intracerebral hemorrhage outcome: apolipoprotein E genotype, hematoma, and edema volumes.” Neurology 53, no. 9 (December 10, 1999): 2176–79. https://doi.org/10.1212/wnl.53.9.2176.
McCarron MO, Hoffmann KL, DeLong DM, Gray L, Saunders AM, Alberts MJ. Intracerebral hemorrhage outcome: apolipoprotein E genotype, hematoma, and edema volumes. Neurology. 1999 Dec 10;53(9):2176–9.
McCarron, M. O., et al. “Intracerebral hemorrhage outcome: apolipoprotein E genotype, hematoma, and edema volumes.” Neurology, vol. 53, no. 9, Dec. 1999, pp. 2176–79. Pubmed, doi:10.1212/wnl.53.9.2176.
McCarron MO, Hoffmann KL, DeLong DM, Gray L, Saunders AM, Alberts MJ. Intracerebral hemorrhage outcome: apolipoprotein E genotype, hematoma, and edema volumes. Neurology. 1999 Dec 10;53(9):2176–2179.
Published In
Neurology
DOI
ISSN
0028-3878
Publication Date
December 10, 1999
Volume
53
Issue
9
Start / End Page
2176 / 2179
Location
United States
Related Subject Headings
- Survival Rate
- Prognosis
- Neurology & Neurosurgery
- Middle Aged
- Male
- Humans
- Hematoma
- Genotype
- Genetic Carrier Screening
- Gene Frequency