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Retinal ganglion cells and axons survive optic nerve transection.

Publication ,  Journal Article
Madison, R; Moore, MR; Sidman, RL
Published in: Int J Neurosci
March 1984

The effects of optic nerve transection on optic axon and retinal cell survival was studied in C57BL/6J mice. The optic nerve was transected either intracranially or intraorbitally . Data are presented which show that an intracranial transection of the optic nerve may be achieved while maintaining the blood supply to the retina. Intraorbital optic nerve transection, however, necessitates destruction of the retinal blood supply. Cell survival in the retinal ganglion cell layer is compared for both transection methods. In addition, electron microscopic evidence is presented which indicates axonal survival in the optic nerve up to at least 90 days following intracranial transection.

Duke Scholars

Published In

Int J Neurosci

DOI

ISSN

0020-7454

Publication Date

March 1984

Volume

23

Issue

1

Start / End Page

15 / 32

Location

England

Related Subject Headings

  • Retinal Vessels
  • Retinal Ganglion Cells
  • Retina
  • Optic Nerve
  • Ophthalmic Artery
  • Neurology & Neurosurgery
  • Nerve Regeneration
  • Mice, Inbred C57BL
  • Mice
  • Male
 

Citation

APA
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ICMJE
MLA
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Madison, R., Moore, M. R., & Sidman, R. L. (1984). Retinal ganglion cells and axons survive optic nerve transection. Int J Neurosci, 23(1), 15–32. https://doi.org/10.3109/00207458408985342
Madison, R., M. R. Moore, and R. L. Sidman. “Retinal ganglion cells and axons survive optic nerve transection.Int J Neurosci 23, no. 1 (March 1984): 15–32. https://doi.org/10.3109/00207458408985342.
Madison R, Moore MR, Sidman RL. Retinal ganglion cells and axons survive optic nerve transection. Int J Neurosci. 1984 Mar;23(1):15–32.
Madison, R., et al. “Retinal ganglion cells and axons survive optic nerve transection.Int J Neurosci, vol. 23, no. 1, Mar. 1984, pp. 15–32. Pubmed, doi:10.3109/00207458408985342.
Madison R, Moore MR, Sidman RL. Retinal ganglion cells and axons survive optic nerve transection. Int J Neurosci. 1984 Mar;23(1):15–32.
Journal cover image

Published In

Int J Neurosci

DOI

ISSN

0020-7454

Publication Date

March 1984

Volume

23

Issue

1

Start / End Page

15 / 32

Location

England

Related Subject Headings

  • Retinal Vessels
  • Retinal Ganglion Cells
  • Retina
  • Optic Nerve
  • Ophthalmic Artery
  • Neurology & Neurosurgery
  • Nerve Regeneration
  • Mice, Inbred C57BL
  • Mice
  • Male