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Zipeprol is a newly abused antitussive with an opioid spectrum and hallucinogenic effects.

Publication ,  Journal Article
Janiri, L; Mannelli, P; Persico, AM; Diodato, S; Tempesta, E
Published in: Drug Alcohol Depend
March 1991

Zipeprol is a non-opioid cough suppressor agent recently abused in Italy. Clinical reports from 30 street abusers show that the drug in high doses has a definite abuse liability and dependence potential. Many of its effects were identical to those induced by opiates, although specific dysperceptive symptoms were commonly reported by patients. Spontaneous withdrawal symptoms were similar to those of opiates. Withdrawal could be also precipitated by naloxone. It is concluded that zipeprol can induce dependence with a mechanism which may be mediated by some types of opioid receptors.

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Published In

Drug Alcohol Depend

DOI

ISSN

0376-8716

Publication Date

March 1991

Volume

27

Issue

2

Start / End Page

121 / 125

Location

Ireland

Related Subject Headings

  • Substance-Related Disorders
  • Substance Withdrawal Syndrome
  • Substance Abuse
  • Rome
  • Piperazines
  • Opioid-Related Disorders
  • Male
  • Humans
  • Hallucinations
  • Female
 

Citation

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Janiri, L., Mannelli, P., Persico, A. M., Diodato, S., & Tempesta, E. (1991). Zipeprol is a newly abused antitussive with an opioid spectrum and hallucinogenic effects. Drug Alcohol Depend, 27(2), 121–125. https://doi.org/10.1016/0376-8716(91)90030-3
Janiri, L., P. Mannelli, A. M. Persico, S. Diodato, and E. Tempesta. “Zipeprol is a newly abused antitussive with an opioid spectrum and hallucinogenic effects.Drug Alcohol Depend 27, no. 2 (March 1991): 121–25. https://doi.org/10.1016/0376-8716(91)90030-3.
Janiri L, Mannelli P, Persico AM, Diodato S, Tempesta E. Zipeprol is a newly abused antitussive with an opioid spectrum and hallucinogenic effects. Drug Alcohol Depend. 1991 Mar;27(2):121–5.
Janiri, L., et al. “Zipeprol is a newly abused antitussive with an opioid spectrum and hallucinogenic effects.Drug Alcohol Depend, vol. 27, no. 2, Mar. 1991, pp. 121–25. Pubmed, doi:10.1016/0376-8716(91)90030-3.
Janiri L, Mannelli P, Persico AM, Diodato S, Tempesta E. Zipeprol is a newly abused antitussive with an opioid spectrum and hallucinogenic effects. Drug Alcohol Depend. 1991 Mar;27(2):121–125.
Journal cover image

Published In

Drug Alcohol Depend

DOI

ISSN

0376-8716

Publication Date

March 1991

Volume

27

Issue

2

Start / End Page

121 / 125

Location

Ireland

Related Subject Headings

  • Substance-Related Disorders
  • Substance Withdrawal Syndrome
  • Substance Abuse
  • Rome
  • Piperazines
  • Opioid-Related Disorders
  • Male
  • Humans
  • Hallucinations
  • Female