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Predictive value of single-fiber electromyography in the extensor digitorum communis muscle of patients with ocular myasthenia gravis: a retrospective study.

Publication ,  Journal Article
Rostedt, A; Saders, LL; Edards, LJ; Massey, JM; Sanders, DB; Stålberg, EV
Published in: J Clin Neuromuscul Dis
September 2000

PURPOSE: To determine if the jitter in the extensor digitorum communis (EDC) muscle in patients with purely ocular myasthenia gravis (OMG) predicts the subsequent development of generalized myasthenic weakness-Methods: Included in this retrospective study were patients who initially had purely ocular manifestations and had been followed for at least 2 years after onset of myasthenic symptoms. The group consisted of 50 patients with purely ocular weakness, 26 of whom later generalized. All underwent single-fiber electromyography (SFEMG) studies in the EDC muscle at the initial examination RESULTS: : Statistical analysis did not demonstrate that the amount of jitter in the EDC muscle predicted the development of generalized myasthenia gravis (GMG). Also, there was no threshold jitter value that predicted generalized weakness. CONCLUSIONS: : SFEMG measurement of jitter in the EDC muscle demonstrates abnormal neuromuscular transmission in many patients with OMG but is not useful in predicting generalization in these patients.

Duke Scholars

Published In

J Clin Neuromuscul Dis

DOI

EISSN

1537-1611

Publication Date

September 2000

Volume

2

Issue

1

Start / End Page

6 / 9

Location

United States

Related Subject Headings

  • Neurology & Neurosurgery
  • 3209 Neurosciences
  • 3202 Clinical sciences
  • 1109 Neurosciences
  • 1103 Clinical Sciences
 

Citation

APA
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MLA
NLM
Rostedt, A., Saders, L. L., Edards, L. J., Massey, J. M., Sanders, D. B., & Stålberg, E. V. (2000). Predictive value of single-fiber electromyography in the extensor digitorum communis muscle of patients with ocular myasthenia gravis: a retrospective study. J Clin Neuromuscul Dis, 2(1), 6–9. https://doi.org/10.1097/00131402-200009000-00003
Rostedt, A., L. L. Saders, L. J. Edards, J. M. Massey, D. B. Sanders, and E. V. Stålberg. “Predictive value of single-fiber electromyography in the extensor digitorum communis muscle of patients with ocular myasthenia gravis: a retrospective study.J Clin Neuromuscul Dis 2, no. 1 (September 2000): 6–9. https://doi.org/10.1097/00131402-200009000-00003.
Rostedt A, Saders LL, Edards LJ, Massey JM, Sanders DB, Stålberg EV. Predictive value of single-fiber electromyography in the extensor digitorum communis muscle of patients with ocular myasthenia gravis: a retrospective study. J Clin Neuromuscul Dis. 2000 Sep;2(1):6–9.
Rostedt, A., et al. “Predictive value of single-fiber electromyography in the extensor digitorum communis muscle of patients with ocular myasthenia gravis: a retrospective study.J Clin Neuromuscul Dis, vol. 2, no. 1, Sept. 2000, pp. 6–9. Pubmed, doi:10.1097/00131402-200009000-00003.
Rostedt A, Saders LL, Edards LJ, Massey JM, Sanders DB, Stålberg EV. Predictive value of single-fiber electromyography in the extensor digitorum communis muscle of patients with ocular myasthenia gravis: a retrospective study. J Clin Neuromuscul Dis. 2000 Sep;2(1):6–9.

Published In

J Clin Neuromuscul Dis

DOI

EISSN

1537-1611

Publication Date

September 2000

Volume

2

Issue

1

Start / End Page

6 / 9

Location

United States

Related Subject Headings

  • Neurology & Neurosurgery
  • 3209 Neurosciences
  • 3202 Clinical sciences
  • 1109 Neurosciences
  • 1103 Clinical Sciences