Effects of Nicotine on Emotional Reactivity in PTSD and Non-PTSD Smokers: Results of a Pilot fMRI Study.
Publication
, Journal Article
Froeliger, B; Crowell Beckham, J; Feldman Dennis, M; Victoria Kozink, R; Joseph McClernon, F
Published in: Adv Pharmacol Sci
2012
There is evidence that individuals with posttraumatic stress disorder (PTSD) may smoke in part to regulate negative affect. This pilot fMRI study examined the effects of nicotine on emotional information processing in smokers with and without PTSD. Across groups, nicotine increased brain activation in response to fearful/angry faces (compared to neutral faces) in ventral caudate. Patch x Group interactions were observed in brain regions involved in emotional and facial feature processing. These preliminary findings suggest that nicotine differentially modulates negative information processing in PTSD and non-PTSD smokers.
Duke Scholars
Published In
Adv Pharmacol Sci
DOI
EISSN
1687-6342
Publication Date
2012
Volume
2012
Start / End Page
265724
Location
United States
Related Subject Headings
- 3214 Pharmacology and pharmaceutical sciences
- 1115 Pharmacology and Pharmaceutical Sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Froeliger, B., Crowell Beckham, J., Feldman Dennis, M., Victoria Kozink, R., & Joseph McClernon, F. (2012). Effects of Nicotine on Emotional Reactivity in PTSD and Non-PTSD Smokers: Results of a Pilot fMRI Study. Adv Pharmacol Sci, 2012, 265724. https://doi.org/10.1155/2012/265724
Froeliger, Brett, Jean Crowell Beckham, Michelle Feldman Dennis, Rachel Victoria Kozink, and Francis Joseph McClernon. “Effects of Nicotine on Emotional Reactivity in PTSD and Non-PTSD Smokers: Results of a Pilot fMRI Study.” Adv Pharmacol Sci 2012 (2012): 265724. https://doi.org/10.1155/2012/265724.
Froeliger B, Crowell Beckham J, Feldman Dennis M, Victoria Kozink R, Joseph McClernon F. Effects of Nicotine on Emotional Reactivity in PTSD and Non-PTSD Smokers: Results of a Pilot fMRI Study. Adv Pharmacol Sci. 2012;2012:265724.
Froeliger, Brett, et al. “Effects of Nicotine on Emotional Reactivity in PTSD and Non-PTSD Smokers: Results of a Pilot fMRI Study.” Adv Pharmacol Sci, vol. 2012, 2012, p. 265724. Pubmed, doi:10.1155/2012/265724.
Froeliger B, Crowell Beckham J, Feldman Dennis M, Victoria Kozink R, Joseph McClernon F. Effects of Nicotine on Emotional Reactivity in PTSD and Non-PTSD Smokers: Results of a Pilot fMRI Study. Adv Pharmacol Sci. 2012;2012:265724.
Published In
Adv Pharmacol Sci
DOI
EISSN
1687-6342
Publication Date
2012
Volume
2012
Start / End Page
265724
Location
United States
Related Subject Headings
- 3214 Pharmacology and pharmaceutical sciences
- 1115 Pharmacology and Pharmaceutical Sciences