Method of lesioning brainstem determines seizure probability.
Publication
, Journal Article
Silver, JM; Bonhaus, DW; McNamara, JO
Published in: J Neurosci Methods
September 1986
We examined 3 different methods of brainstem lesioning to assess their propensities to evoke seizures in the early postoperative period. Lesioning by electrolysis or microinjection of the neurotoxin, N-methyl-D,L-aspartate, caused seizures, but lesioning by thermocoagulation (radiofrequency current) did not. In paradigms in which postoperative lesion-induced seizures could confound interpretation of experimental results, the thermocoagulative method offers an important advantage.
Duke Scholars
Published In
J Neurosci Methods
DOI
ISSN
0165-0270
Publication Date
September 1986
Volume
17
Issue
4
Start / End Page
303 / 310
Location
Netherlands
Related Subject Headings
- Seizures
- Rats, Inbred Strains
- Rats
- Neurology & Neurosurgery
- Neurology
- N-Methylaspartate
- Male
- Hot Temperature
- Electric Injuries
- Brain Stem
Citation
APA
Chicago
ICMJE
MLA
NLM
Silver, J. M., Bonhaus, D. W., & McNamara, J. O. (1986). Method of lesioning brainstem determines seizure probability. J Neurosci Methods, 17(4), 303–310. https://doi.org/10.1016/0165-0270(86)90131-7
Silver, J. M., D. W. Bonhaus, and J. O. McNamara. “Method of lesioning brainstem determines seizure probability.” J Neurosci Methods 17, no. 4 (September 1986): 303–10. https://doi.org/10.1016/0165-0270(86)90131-7.
Silver JM, Bonhaus DW, McNamara JO. Method of lesioning brainstem determines seizure probability. J Neurosci Methods. 1986 Sep;17(4):303–10.
Silver, J. M., et al. “Method of lesioning brainstem determines seizure probability.” J Neurosci Methods, vol. 17, no. 4, Sept. 1986, pp. 303–10. Pubmed, doi:10.1016/0165-0270(86)90131-7.
Silver JM, Bonhaus DW, McNamara JO. Method of lesioning brainstem determines seizure probability. J Neurosci Methods. 1986 Sep;17(4):303–310.
Published In
J Neurosci Methods
DOI
ISSN
0165-0270
Publication Date
September 1986
Volume
17
Issue
4
Start / End Page
303 / 310
Location
Netherlands
Related Subject Headings
- Seizures
- Rats, Inbred Strains
- Rats
- Neurology & Neurosurgery
- Neurology
- N-Methylaspartate
- Male
- Hot Temperature
- Electric Injuries
- Brain Stem