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Changes in dynorphin, enkephalin and cholecystokinin content of hippocampus and substantia nigra after amygdala kindling.

Publication ,  Journal Article
Iadarola, MJ; Shin, C; McNamara, JO; Yang, HY
Published in: Brain Res
February 12, 1986

Amygdaloid kindling of rats produced an increase in hippocampal Met5-enkephalin-Arg6-Gly7-Leu8 and cholecystokinin immunoreactivities and simultaneously a decrease in dynorphin A1-8 content. In substantia nigra Met5-enkephalin-Arg6-Gly7-Leu8 was increased and no change was observed in dynorphin A1-8 content. These data suggest that specific alterations of neuropeptides in limbic and extrapyramidal circuits are prominent manifestations of the kindling process or kindled seizures.

Duke Scholars

Published In

Brain Res

DOI

ISSN

0006-8993

Publication Date

February 12, 1986

Volume

365

Issue

1

Start / End Page

185 / 191

Location

Netherlands

Related Subject Headings

  • Substantia Nigra
  • Rats, Inbred Strains
  • Rats
  • Peptides
  • Peptide Fragments
  • Neurology & Neurosurgery
  • Male
  • Kindling, Neurologic
  • Hippocampus
  • Enkephalin, Methionine
 

Citation

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Iadarola, M. J., Shin, C., McNamara, J. O., & Yang, H. Y. (1986). Changes in dynorphin, enkephalin and cholecystokinin content of hippocampus and substantia nigra after amygdala kindling. Brain Res, 365(1), 185–191. https://doi.org/10.1016/0006-8993(86)90738-9
Iadarola, M. J., C. Shin, J. O. McNamara, and H. Y. Yang. “Changes in dynorphin, enkephalin and cholecystokinin content of hippocampus and substantia nigra after amygdala kindling.Brain Res 365, no. 1 (February 12, 1986): 185–91. https://doi.org/10.1016/0006-8993(86)90738-9.
Iadarola MJ, Shin C, McNamara JO, Yang HY. Changes in dynorphin, enkephalin and cholecystokinin content of hippocampus and substantia nigra after amygdala kindling. Brain Res. 1986 Feb 12;365(1):185–91.
Iadarola, M. J., et al. “Changes in dynorphin, enkephalin and cholecystokinin content of hippocampus and substantia nigra after amygdala kindling.Brain Res, vol. 365, no. 1, Feb. 1986, pp. 185–91. Pubmed, doi:10.1016/0006-8993(86)90738-9.
Iadarola MJ, Shin C, McNamara JO, Yang HY. Changes in dynorphin, enkephalin and cholecystokinin content of hippocampus and substantia nigra after amygdala kindling. Brain Res. 1986 Feb 12;365(1):185–191.
Journal cover image

Published In

Brain Res

DOI

ISSN

0006-8993

Publication Date

February 12, 1986

Volume

365

Issue

1

Start / End Page

185 / 191

Location

Netherlands

Related Subject Headings

  • Substantia Nigra
  • Rats, Inbred Strains
  • Rats
  • Peptides
  • Peptide Fragments
  • Neurology & Neurosurgery
  • Male
  • Kindling, Neurologic
  • Hippocampus
  • Enkephalin, Methionine