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Hepato-biliary late effects in survivors of childhood and adolescent cancer: a report from the Children's Oncology Group.

Publication ,  Journal Article
Castellino, S; Muir, A; Shah, A; Shope, S; McMullen, K; Ruble, K; Barber, A; Davidoff, A; Hudson, MM
Published in: Pediatr Blood Cancer
May 2010

Curative therapy for childhood and adolescent cancer translates to 1 in 640 young adults being a survivor of cancer. Although acute hepato-biliary toxicity occurs commonly during pediatric cancer therapy, the impact of antineoplastic therapy on long-term liver health in childhood/adolescent cancer survivors is unknown. This article reviews the medical literature on late liver dysfunction following treatment for childhood/adolescent cancer. We also outline the Children's Oncology Group (COG) guidelines for screening and follow-up of hepato-biliary sequelae. As the population of survivors grow and age, vigilance for risks to hepatic health needs to continue based on specific exposures during curative cancer therapy.

Duke Scholars

Published In

Pediatr Blood Cancer

DOI

EISSN

1545-5017

Publication Date

May 2010

Volume

54

Issue

5

Start / End Page

663 / 669

Location

United States

Related Subject Headings

  • Transfusion Reaction
  • Survivors
  • Stem Cell Transplantation
  • Radiotherapy
  • Practice Guidelines as Topic
  • Oncology & Carcinogenesis
  • Neoplasms
  • Mass Screening
  • Liver Diseases
  • Humans
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Castellino, S., Muir, A., Shah, A., Shope, S., McMullen, K., Ruble, K., … Hudson, M. M. (2010). Hepato-biliary late effects in survivors of childhood and adolescent cancer: a report from the Children's Oncology Group. Pediatr Blood Cancer, 54(5), 663–669. https://doi.org/10.1002/pbc.22265
Castellino, Sharon, Andrew Muir, Ami Shah, Sheila Shope, Kevin McMullen, Kathy Ruble, Ashley Barber, Andrew Davidoff, and Melissa M. Hudson. “Hepato-biliary late effects in survivors of childhood and adolescent cancer: a report from the Children's Oncology Group.Pediatr Blood Cancer 54, no. 5 (May 2010): 663–69. https://doi.org/10.1002/pbc.22265.
Castellino S, Muir A, Shah A, Shope S, McMullen K, Ruble K, et al. Hepato-biliary late effects in survivors of childhood and adolescent cancer: a report from the Children's Oncology Group. Pediatr Blood Cancer. 2010 May;54(5):663–9.
Castellino, Sharon, et al. “Hepato-biliary late effects in survivors of childhood and adolescent cancer: a report from the Children's Oncology Group.Pediatr Blood Cancer, vol. 54, no. 5, May 2010, pp. 663–69. Pubmed, doi:10.1002/pbc.22265.
Castellino S, Muir A, Shah A, Shope S, McMullen K, Ruble K, Barber A, Davidoff A, Hudson MM. Hepato-biliary late effects in survivors of childhood and adolescent cancer: a report from the Children's Oncology Group. Pediatr Blood Cancer. 2010 May;54(5):663–669.
Journal cover image

Published In

Pediatr Blood Cancer

DOI

EISSN

1545-5017

Publication Date

May 2010

Volume

54

Issue

5

Start / End Page

663 / 669

Location

United States

Related Subject Headings

  • Transfusion Reaction
  • Survivors
  • Stem Cell Transplantation
  • Radiotherapy
  • Practice Guidelines as Topic
  • Oncology & Carcinogenesis
  • Neoplasms
  • Mass Screening
  • Liver Diseases
  • Humans