Modeling in the Bioelectric Stimulation Unit
The research program of Unit 1.1C, Modeling in Bioelectric Stimulation, of the National Science Foundation/Engineering Research Center (NSF/ERC) is described. The modeling effort is centered around problems associated with cardiac electric fields, those arising naturally during propagation of the activation impulse, and those induced artificially by pacing, defibrillation, and impedance measurements. In the area of forward and inverse problems, the major accomplishments are (1) development of a three-dimensional model which includes all major inhomogeneities of the torso with their realistic geometries, (2) derivation of an analytic relationship between the potential and the thickness of the skeletal muscle layer, and (3) the experimental verification of endocardial potentials estimated from a model with potentials obtained experimentally.
