
Rectal cancer: the sphincter-sparing approach.
Publication
, Journal Article
Ota, DM; Jacobs, L; Kuvshinoff, B
Published in: Surg Clin North Am
October 2002
There is considerable skepticism regarding sphincter-preserving surgery for rectal cancer, and 40% to 60% APR rates are reported in many prospective studies. Despite radical surgery, 20% positive margin rates are frequently reported. Rectal carcinoma responds to preoperative chemoradiation therapy with a 10% to 15% pathologic complete response rate. Preoperative therapy offers an opportunity to reduce the positive margin rate and to reduce the APR rate. Because there is significant tumor regression with preoperative therapy, distal margins of less 1 cm are acceptable and do not result in suture line recurrence. APR rate of less than 10% is feasible and better chemotherapy with radiation therapy will reduce the APR to less than 5%.
Duke Scholars
Published In
Surg Clin North Am
DOI
ISSN
0039-6109
Publication Date
October 2002
Volume
82
Issue
5
Start / End Page
983 / 993
Location
United States
Related Subject Headings
- Surgery
- Rectal Neoplasms
- Plastic Surgery Procedures
- Neoplasm Invasiveness
- Humans
- Combined Modality Therapy
- Antineoplastic Agents
- Anastomosis, Surgical
- Anal Canal
- 3202 Clinical sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Ota, D. M., Jacobs, L., & Kuvshinoff, B. (2002). Rectal cancer: the sphincter-sparing approach. Surg Clin North Am, 82(5), 983–993. https://doi.org/10.1016/s0039-6109(02)00048-8
Ota, David M., Lisa Jacobs, and Boris Kuvshinoff. “Rectal cancer: the sphincter-sparing approach.” Surg Clin North Am 82, no. 5 (October 2002): 983–93. https://doi.org/10.1016/s0039-6109(02)00048-8.
Ota DM, Jacobs L, Kuvshinoff B. Rectal cancer: the sphincter-sparing approach. Surg Clin North Am. 2002 Oct;82(5):983–93.
Ota, David M., et al. “Rectal cancer: the sphincter-sparing approach.” Surg Clin North Am, vol. 82, no. 5, Oct. 2002, pp. 983–93. Pubmed, doi:10.1016/s0039-6109(02)00048-8.
Ota DM, Jacobs L, Kuvshinoff B. Rectal cancer: the sphincter-sparing approach. Surg Clin North Am. 2002 Oct;82(5):983–993.

Published In
Surg Clin North Am
DOI
ISSN
0039-6109
Publication Date
October 2002
Volume
82
Issue
5
Start / End Page
983 / 993
Location
United States
Related Subject Headings
- Surgery
- Rectal Neoplasms
- Plastic Surgery Procedures
- Neoplasm Invasiveness
- Humans
- Combined Modality Therapy
- Antineoplastic Agents
- Anastomosis, Surgical
- Anal Canal
- 3202 Clinical sciences