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Advances in the treatment of inflammatory arthritis.

Publication ,  Journal Article
Pisetsky, DS; Ward, MM
Published in: Best Pract Res Clin Rheumatol
April 2012

The inflammatory arthritides are a diverse group of conditions characterised by joint inflammation which can lead to pain, deformity and disability. Of these diseases, rheumatoid arthritis (RA) and spondyloarthritis are two of the most common. While the clinical and demographic features of these diseases differ, the central role of inflammation in their pathogenesis has allowed the development of highly effective treatment strategies with wide applicability. These strategies include the use of biological agents which target the cytokine tumour necrosis factor (TNF), a key mediator of inflammation. With the advent of effective agents, therapy has become more aggressive, reducing disease activity and allowing, at least in RA, remission in many patients. While the array of available effective treatments is extensive, the use of objective measures of disease activity can guide treatment decisions (treat to target) and lead to improved outcomes.

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Published In

Best Pract Res Clin Rheumatol

DOI

EISSN

1532-1770

Publication Date

April 2012

Volume

26

Issue

2

Start / End Page

251 / 261

Location

Netherlands

Related Subject Headings

  • Tumor Necrosis Factor-alpha
  • Inflammation
  • Humans
  • Biological Products
  • Arthritis, Rheumatoid
  • Arthritis & Rheumatology
  • Arthritis
  • Antirheumatic Agents
  • 3202 Clinical sciences
  • 1117 Public Health and Health Services
 

Citation

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Pisetsky, D. S., & Ward, M. M. (2012). Advances in the treatment of inflammatory arthritis. Best Pract Res Clin Rheumatol, 26(2), 251–261. https://doi.org/10.1016/j.berh.2012.03.001
Pisetsky, David S., and Michael M. Ward. “Advances in the treatment of inflammatory arthritis.Best Pract Res Clin Rheumatol 26, no. 2 (April 2012): 251–61. https://doi.org/10.1016/j.berh.2012.03.001.
Pisetsky DS, Ward MM. Advances in the treatment of inflammatory arthritis. Best Pract Res Clin Rheumatol. 2012 Apr;26(2):251–61.
Pisetsky, David S., and Michael M. Ward. “Advances in the treatment of inflammatory arthritis.Best Pract Res Clin Rheumatol, vol. 26, no. 2, Apr. 2012, pp. 251–61. Pubmed, doi:10.1016/j.berh.2012.03.001.
Pisetsky DS, Ward MM. Advances in the treatment of inflammatory arthritis. Best Pract Res Clin Rheumatol. 2012 Apr;26(2):251–261.
Journal cover image

Published In

Best Pract Res Clin Rheumatol

DOI

EISSN

1532-1770

Publication Date

April 2012

Volume

26

Issue

2

Start / End Page

251 / 261

Location

Netherlands

Related Subject Headings

  • Tumor Necrosis Factor-alpha
  • Inflammation
  • Humans
  • Biological Products
  • Arthritis, Rheumatoid
  • Arthritis & Rheumatology
  • Arthritis
  • Antirheumatic Agents
  • 3202 Clinical sciences
  • 1117 Public Health and Health Services