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PKM2 and the tricky balance of growth and energy in cancer.

Publication ,  Journal Article
Macintyre, AN; Rathmell, JC
Published in: Mol Cell
June 24, 2011

In this issue of Molecular Cell, Lv et al. (2011) identify a novel feedback mechanism in which increased glycolysis induces the acetylation and chaperone-mediated autophagic degradation of the glycolytic regulator PKM2, revealing a novel metabolic feedback loop that drives tumor growth.

Duke Scholars

Published In

Mol Cell

DOI

EISSN

1097-4164

Publication Date

June 24, 2011

Volume

42

Issue

6

Start / End Page

713 / 714

Location

United States

Related Subject Headings

  • Developmental Biology
  • 42 Health sciences
  • 32 Biomedical and clinical sciences
  • 31 Biological sciences
  • 11 Medical and Health Sciences
  • 06 Biological Sciences
 

Citation

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Macintyre, A. N., & Rathmell, J. C. (2011). PKM2 and the tricky balance of growth and energy in cancer. Mol Cell, 42(6), 713–714. https://doi.org/10.1016/j.molcel.2011.06.003
Macintyre, Andrew N., and Jeffrey C. Rathmell. “PKM2 and the tricky balance of growth and energy in cancer.Mol Cell 42, no. 6 (June 24, 2011): 713–14. https://doi.org/10.1016/j.molcel.2011.06.003.
Macintyre AN, Rathmell JC. PKM2 and the tricky balance of growth and energy in cancer. Mol Cell. 2011 Jun 24;42(6):713–4.
Macintyre, Andrew N., and Jeffrey C. Rathmell. “PKM2 and the tricky balance of growth and energy in cancer.Mol Cell, vol. 42, no. 6, June 2011, pp. 713–14. Pubmed, doi:10.1016/j.molcel.2011.06.003.
Macintyre AN, Rathmell JC. PKM2 and the tricky balance of growth and energy in cancer. Mol Cell. 2011 Jun 24;42(6):713–714.
Journal cover image

Published In

Mol Cell

DOI

EISSN

1097-4164

Publication Date

June 24, 2011

Volume

42

Issue

6

Start / End Page

713 / 714

Location

United States

Related Subject Headings

  • Developmental Biology
  • 42 Health sciences
  • 32 Biomedical and clinical sciences
  • 31 Biological sciences
  • 11 Medical and Health Sciences
  • 06 Biological Sciences