Cytotoxic, antifouling bromotyramines: a synthetic study on simple marine natural products and Their analogues.
Publication
, Journal Article
Schoenfeld, RC; Conova, S; Rittschof, D; Ganem, B
Published in: Bioorganic & medicinal chemistry letters
March 2002
Synthesis and biological evaluation of two naturally-occurring bromotyramines, moloka'iamine 1 and 3,5-dibromo-4-methoxy-beta-phenethylamine 2, together with several analogues, have been completed. Bromotyramine 2 is cytotoxic, and was found to be a potent antifoulant. Analogues 15 and 16 also displayed significant cytotoxic and antifouling activities.
Duke Scholars
Published In
Bioorganic & medicinal chemistry letters
DOI
EISSN
1464-3405
ISSN
0960-894X
Publication Date
March 2002
Volume
12
Issue
5
Start / End Page
823 / 825
Related Subject Headings
- Tyramine
- Tumor Cells, Cultured
- Molecular Structure
- Medicinal & Biomolecular Chemistry
- Marine Biology
- Humans
- Drug Screening Assays, Antitumor
- Cell Survival
- Bacteria
- Antibiotics, Antineoplastic
Citation
APA
Chicago
ICMJE
MLA
NLM
Schoenfeld, R. C., Conova, S., Rittschof, D., & Ganem, B. (2002). Cytotoxic, antifouling bromotyramines: a synthetic study on simple marine natural products and Their analogues. Bioorganic & Medicinal Chemistry Letters, 12(5), 823–825. https://doi.org/10.1016/s0960-894x(02)00022-7
Schoenfeld, Ryan C., Susan Conova, Daniel Rittschof, and Bruce Ganem. “Cytotoxic, antifouling bromotyramines: a synthetic study on simple marine natural products and Their analogues.” Bioorganic & Medicinal Chemistry Letters 12, no. 5 (March 2002): 823–25. https://doi.org/10.1016/s0960-894x(02)00022-7.
Schoenfeld RC, Conova S, Rittschof D, Ganem B. Cytotoxic, antifouling bromotyramines: a synthetic study on simple marine natural products and Their analogues. Bioorganic & medicinal chemistry letters. 2002 Mar;12(5):823–5.
Schoenfeld, Ryan C., et al. “Cytotoxic, antifouling bromotyramines: a synthetic study on simple marine natural products and Their analogues.” Bioorganic & Medicinal Chemistry Letters, vol. 12, no. 5, Mar. 2002, pp. 823–25. Epmc, doi:10.1016/s0960-894x(02)00022-7.
Schoenfeld RC, Conova S, Rittschof D, Ganem B. Cytotoxic, antifouling bromotyramines: a synthetic study on simple marine natural products and Their analogues. Bioorganic & medicinal chemistry letters. 2002 Mar;12(5):823–825.
Published In
Bioorganic & medicinal chemistry letters
DOI
EISSN
1464-3405
ISSN
0960-894X
Publication Date
March 2002
Volume
12
Issue
5
Start / End Page
823 / 825
Related Subject Headings
- Tyramine
- Tumor Cells, Cultured
- Molecular Structure
- Medicinal & Biomolecular Chemistry
- Marine Biology
- Humans
- Drug Screening Assays, Antitumor
- Cell Survival
- Bacteria
- Antibiotics, Antineoplastic