
Non-neurogenic stimulation of adrenomedullary secretion during endotoxicosis in the one day old rat.
Publication
, Journal Article
Seidler, FJ; Mills, E
Published in: Life Sci
1989
In both newborn and twenty day old rats, bacterial (S. enteritidis) endotoxin caused a marked decrease in adrenal epinephrine and norepinephrine. Catecholamine release was prevented by ganglionic blockade in 20 day old, but not 1 day old animals, indicating that the release in the neonatal rat is "non-neurogenic." The amount released was physiologically significant: equivalent to 20 micrograms/kg by i.v. administration. Two possible mechanism known to promote non-neurogenic secretion are hypoxia or histamine release, both of which can occur during endotoxicosis.
Duke Scholars
Published In
Life Sci
DOI
ISSN
0024-3205
Publication Date
1989
Volume
45
Issue
5
Start / End Page
379 / 381
Location
Netherlands
Related Subject Headings
- Salmonella enteritidis
- Reference Values
- Rats, Inbred Strains
- Rats
- Pharmacology & Pharmacy
- Norepinephrine
- Epinephrine
- Endotoxins
- Chlorisondamine
- Animals, Newborn
Citation
APA
Chicago
ICMJE
MLA
NLM
Seidler, F. J., & Mills, E. (1989). Non-neurogenic stimulation of adrenomedullary secretion during endotoxicosis in the one day old rat. Life Sci, 45(5), 379–381. https://doi.org/10.1016/0024-3205(89)90623-1
Seidler, F. J., and E. Mills. “Non-neurogenic stimulation of adrenomedullary secretion during endotoxicosis in the one day old rat.” Life Sci 45, no. 5 (1989): 379–81. https://doi.org/10.1016/0024-3205(89)90623-1.
Seidler FJ, Mills E. Non-neurogenic stimulation of adrenomedullary secretion during endotoxicosis in the one day old rat. Life Sci. 1989;45(5):379–81.
Seidler, F. J., and E. Mills. “Non-neurogenic stimulation of adrenomedullary secretion during endotoxicosis in the one day old rat.” Life Sci, vol. 45, no. 5, 1989, pp. 379–81. Pubmed, doi:10.1016/0024-3205(89)90623-1.
Seidler FJ, Mills E. Non-neurogenic stimulation of adrenomedullary secretion during endotoxicosis in the one day old rat. Life Sci. 1989;45(5):379–381.

Published In
Life Sci
DOI
ISSN
0024-3205
Publication Date
1989
Volume
45
Issue
5
Start / End Page
379 / 381
Location
Netherlands
Related Subject Headings
- Salmonella enteritidis
- Reference Values
- Rats, Inbred Strains
- Rats
- Pharmacology & Pharmacy
- Norepinephrine
- Epinephrine
- Endotoxins
- Chlorisondamine
- Animals, Newborn