Casein kinase 1: Complexity in the family.
Publication
, Journal Article
Cheong, JK; Virshup, DM
Published in: Int J Biochem Cell Biol
April 2011
The CK1 family of serine/threonine kinases regulates diverse cellular processes, through binding to and phosphorylation a myriad of protein substrates. CK1 prefers substrates primed by prior phosphorylation, and works closely with other kinases in the Wnt pathway. CK1 is itself regulated by posttranslational modification, including autophosphorylation. We provide a brief overview of the fundamentals of CK1 biology with an emphasis on scaffold binding and kinase regulation in Wnt signaling and circadian rhythms.
Duke Scholars
Published In
Int J Biochem Cell Biol
DOI
EISSN
1878-5875
Publication Date
April 2011
Volume
43
Issue
4
Start / End Page
465 / 469
Location
Netherlands
Related Subject Headings
- Neoplasms
- Humans
- Gene Expression Regulation, Enzymologic
- Enzyme Activation
- Circadian Rhythm
- Casein Kinase I
- Biochemistry & Molecular Biology
- Animals
- 3205 Medical biochemistry and metabolomics
- 3101 Biochemistry and cell biology
Citation
APA
Chicago
ICMJE
MLA
NLM
Cheong, J. K., & Virshup, D. M. (2011). Casein kinase 1: Complexity in the family. Int J Biochem Cell Biol, 43(4), 465–469. https://doi.org/10.1016/j.biocel.2010.12.004
Cheong, Jit Kong, and David M. Virshup. “Casein kinase 1: Complexity in the family.” Int J Biochem Cell Biol 43, no. 4 (April 2011): 465–69. https://doi.org/10.1016/j.biocel.2010.12.004.
Cheong JK, Virshup DM. Casein kinase 1: Complexity in the family. Int J Biochem Cell Biol. 2011 Apr;43(4):465–9.
Cheong, Jit Kong, and David M. Virshup. “Casein kinase 1: Complexity in the family.” Int J Biochem Cell Biol, vol. 43, no. 4, Apr. 2011, pp. 465–69. Pubmed, doi:10.1016/j.biocel.2010.12.004.
Cheong JK, Virshup DM. Casein kinase 1: Complexity in the family. Int J Biochem Cell Biol. 2011 Apr;43(4):465–469.
Published In
Int J Biochem Cell Biol
DOI
EISSN
1878-5875
Publication Date
April 2011
Volume
43
Issue
4
Start / End Page
465 / 469
Location
Netherlands
Related Subject Headings
- Neoplasms
- Humans
- Gene Expression Regulation, Enzymologic
- Enzyme Activation
- Circadian Rhythm
- Casein Kinase I
- Biochemistry & Molecular Biology
- Animals
- 3205 Medical biochemistry and metabolomics
- 3101 Biochemistry and cell biology