Skip to main content

Effects of neuronal PIK3C3/Vps34 deletion on autophagy and beyond.

Publication ,  Journal Article
Zhou, X; Wang, F
Published in: Autophagy
August 2010

PIK3C3/Vps34 plays important roles in the endocytic and autophagic pathways, both of which are essential for maintaining neuronal integrity. However, it is unclear how inactivating PIK3C3 may affect neuronal endosomal versus autophagic processes in vivo. We generated a conditional null allele of the Pik3c3 gene in mouse, and specifically deleted it in postmitotic sensory neurons. Subsequent analyses reveal several interesting and surprising findings.

Duke Scholars

Published In

Autophagy

DOI

EISSN

1554-8635

Publication Date

August 2010

Volume

6

Issue

6

Start / End Page

798 / 799

Location

United States

Related Subject Headings

  • Sensory Receptor Cells
  • Phosphatidylinositol Phosphates
  • Phosphatidylinositol 3-Kinase
  • Phenotype
  • Phagosomes
  • Mice, Knockout
  • Mice
  • Membrane Proteins
  • Gene Deletion
  • Enzyme Activation
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Zhou, X., & Wang, F. (2010). Effects of neuronal PIK3C3/Vps34 deletion on autophagy and beyond. Autophagy, 6(6), 798–799. https://doi.org/10.4161/auto.6.6.12511
Zhou, Xiang, and Fan Wang. “Effects of neuronal PIK3C3/Vps34 deletion on autophagy and beyond.Autophagy 6, no. 6 (August 2010): 798–99. https://doi.org/10.4161/auto.6.6.12511.
Zhou X, Wang F. Effects of neuronal PIK3C3/Vps34 deletion on autophagy and beyond. Autophagy. 2010 Aug;6(6):798–9.
Zhou, Xiang, and Fan Wang. “Effects of neuronal PIK3C3/Vps34 deletion on autophagy and beyond.Autophagy, vol. 6, no. 6, Aug. 2010, pp. 798–99. Pubmed, doi:10.4161/auto.6.6.12511.
Zhou X, Wang F. Effects of neuronal PIK3C3/Vps34 deletion on autophagy and beyond. Autophagy. 2010 Aug;6(6):798–799.

Published In

Autophagy

DOI

EISSN

1554-8635

Publication Date

August 2010

Volume

6

Issue

6

Start / End Page

798 / 799

Location

United States

Related Subject Headings

  • Sensory Receptor Cells
  • Phosphatidylinositol Phosphates
  • Phosphatidylinositol 3-Kinase
  • Phenotype
  • Phagosomes
  • Mice, Knockout
  • Mice
  • Membrane Proteins
  • Gene Deletion
  • Enzyme Activation