Scholars@Duke publication: Early sensory information processes are enhanced on visual oddball and S1-S2 tasks in Parkinson's disease: a visual event-related potentials study.

Early sensory information processes are enhanced on visual oddball and S1-S2 tasks in Parkinson's disease: a visual event-related potentials study.

Publication , Journal Article

Li, M; Kuroiwa, Y; Wang, L; Kamitani, T; Takahashi, T; Suzuki, Y; Omoto, S

Published in: Parkinsonism Relat Disord

August 2003

To observe sensory and cognitive information processing in Parkinson's disease (PD), 34 PD patients and 26 controls were investigated. A visual oddball paradigm and an S1-S2 paradigm were employed to record the early (P1, N1, P2) and late (N2, P3) event-related potentials (ERPs) at Cz, Pz and Oz. Results showed: (1) enlarged P1 amplitude at all electrode locations on both tasks, (2) shortened N1 latency and enlarged P2 amplitude at Oz on both tasks, (3) enlarged N1 amplitude at Cz during an oddball paradigm, (4) delayed N2 latency and decreased N2, P3 amplitude on both tasks, and (5) delayed P3 latency and reaction time during the S1-S2 paradigm. Abnormal ERP changes were correlated with worsened scores on Wechsler Adult Intelligence Scale-Revised and motor dysfunction scales in PD. We surmise overactive aspects or failed inhibitory modulation of sensory information processing in the early ERP stage and deficient cognitive information processing during the late ERP stage in PD.

Duke Scholars

Author Lihong Wang Psychiatry & Behavioral Sciences, Adult Psychiatry & Psychol ...

Published In

Parkinsonism Relat Disord

DOI

10.1016/s1353-8020(02)00094-9

ISSN

1353-8020

Publication Date

August 2003

Volume

Issue

Start / End Page

329 / 340

Location

England

Related Subject Headings

Task Performance and Analysis
Reaction Time
Parkinson Disease
Neuropsychological Tests
Neurology & Neurosurgery
Middle Aged
Male
Humans
Female
Evoked Potentials, Visual

Citation

APA

Chicago

ICMJE

MLA

NLM

Li, M., Kuroiwa, Y., Wang, L., Kamitani, T., Takahashi, T., Suzuki, Y., & Omoto, S. (2003). Early sensory information processes are enhanced on visual oddball and S1-S2 tasks in Parkinson's disease: a visual event-related potentials study. Parkinsonism Relat Disord, 9(6), 329–340. https://doi.org/10.1016/s1353-8020(02)00094-9

Li, Mei, Yoshiyuki Kuroiwa, Lihong Wang, Toshiaki Kamitani, Tatsuya Takahashi, Yume Suzuki, and Shu Omoto. “Early sensory information processes are enhanced on visual oddball and S1-S2 tasks in Parkinson's disease: a visual event-related potentials study.” Parkinsonism Relat Disord 9, no. 6 (August 2003): 329–40. https://doi.org/10.1016/s1353-8020(02)00094-9.

Li M, Kuroiwa Y, Wang L, Kamitani T, Takahashi T, Suzuki Y, et al. Early sensory information processes are enhanced on visual oddball and S1-S2 tasks in Parkinson's disease: a visual event-related potentials study. Parkinsonism Relat Disord. 2003 Aug;9(6):329–40.

Li, Mei, et al. “Early sensory information processes are enhanced on visual oddball and S1-S2 tasks in Parkinson's disease: a visual event-related potentials study.” Parkinsonism Relat Disord, vol. 9, no. 6, Aug. 2003, pp. 329–40. Pubmed, doi:10.1016/s1353-8020(02)00094-9.

Li M, Kuroiwa Y, Wang L, Kamitani T, Takahashi T, Suzuki Y, Omoto S. Early sensory information processes are enhanced on visual oddball and S1-S2 tasks in Parkinson's disease: a visual event-related potentials study. Parkinsonism Relat Disord. 2003 Aug;9(6):329–340.