
Smads "freeze" when they ski.
Publication
, Journal Article
Frederick, JP; Wang, X-F
Published in: Structure
December 2002
The transforming growth factor-beta (TGF-beta) signal is manifest through activated heteromeric Smad complex-mediated transcriptional modulation of target genes that translates into diverse, context-specific biologic effects, such as the potent TGF-beta-initiated cytostatic program. The TGF-beta pathway is effectively antagonized through the direct binding and subsequent repression of activated Smad heteromeric complexes by the Ski family of proto-oncoproteins.
Duke Scholars
Published In
Structure
DOI
ISSN
0969-2126
Publication Date
December 2002
Volume
10
Issue
12
Start / End Page
1607 / 1611
Location
United States
Related Subject Headings
- Transforming Growth Factor beta
- Trans-Activators
- Smad Proteins
- Signal Transduction
- DNA-Binding Proteins
- Biophysics
- 34 Chemical sciences
- 31 Biological sciences
- 08 Information and Computing Sciences
- 06 Biological Sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Frederick, J. P., & Wang, X.-F. (2002). Smads "freeze" when they ski. Structure, 10(12), 1607–1611. https://doi.org/10.1016/s0969-2126(02)00914-0
Frederick, Joshua P., and Xiao-Fan Wang. “Smads "freeze" when they ski.” Structure 10, no. 12 (December 2002): 1607–11. https://doi.org/10.1016/s0969-2126(02)00914-0.
Frederick JP, Wang X-F. Smads "freeze" when they ski. Structure. 2002 Dec;10(12):1607–11.
Frederick, Joshua P., and Xiao-Fan Wang. “Smads "freeze" when they ski.” Structure, vol. 10, no. 12, Dec. 2002, pp. 1607–11. Pubmed, doi:10.1016/s0969-2126(02)00914-0.
Frederick JP, Wang X-F. Smads "freeze" when they ski. Structure. 2002 Dec;10(12):1607–1611.

Published In
Structure
DOI
ISSN
0969-2126
Publication Date
December 2002
Volume
10
Issue
12
Start / End Page
1607 / 1611
Location
United States
Related Subject Headings
- Transforming Growth Factor beta
- Trans-Activators
- Smad Proteins
- Signal Transduction
- DNA-Binding Proteins
- Biophysics
- 34 Chemical sciences
- 31 Biological sciences
- 08 Information and Computing Sciences
- 06 Biological Sciences