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Isolating quantum coherences in structural imaging using intermolecular double-quantum coherence MRI.

Publication ,  Journal Article
Chin, C-L; Tang, X; Bouchard, L-S; Saha, PK; Warren, WS; Wehrli, FW
Published in: Journal of magnetic resonance (San Diego, Calif. : 1997)
December 2003

Intermolecular multiple-quantum coherence (iMQC) MR imaging provides a fundamentally different contrast mechanism. It allows probing tissue microstructure by tuning the direction and strength of the correlation gradient. However, iMQC images of a specific quantum-coherence can easily be contaminated by leakage signals from undesired quantum coherences (zero, single, and triple quantum coherence in this work). Using a modified double-quantum CRAZED imaging sequence, we show that signals originating from various coherence orders (M=0, 1, 2, 3) can be predicted in k-space and effectively isolated by means of a four-step phase cycling scheme and judicious choice of flip angles. Finally, preliminary data suggest the method to be able to provide information on trabecular bone architecture such as regional mean trabecular plate separation.

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Published In

Journal of magnetic resonance (San Diego, Calif. : 1997)

DOI

EISSN

1096-0856

ISSN

1090-7807

Publication Date

December 2003

Volume

165

Issue

2

Start / End Page

309 / 314

Related Subject Headings

  • Surgery, Computer-Assisted
  • Signal Processing, Computer-Assisted
  • Radius
  • Quantum Theory
  • Magnetic Resonance Imaging
  • Humans
  • Feasibility Studies
  • Crystallography
  • Biophysics
  • Algorithms
 

Citation

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Chin, C.-L., Tang, X., Bouchard, L.-S., Saha, P. K., Warren, W. S., & Wehrli, F. W. (2003). Isolating quantum coherences in structural imaging using intermolecular double-quantum coherence MRI. Journal of Magnetic Resonance (San Diego, Calif. : 1997), 165(2), 309–314. https://doi.org/10.1016/j.jmr.2003.08.007
Chin, Chih-Liang, Xiaoping Tang, Louis-S Bouchard, Punam K. Saha, Warren S. Warren, and Felix W. Wehrli. “Isolating quantum coherences in structural imaging using intermolecular double-quantum coherence MRI.Journal of Magnetic Resonance (San Diego, Calif. : 1997) 165, no. 2 (December 2003): 309–14. https://doi.org/10.1016/j.jmr.2003.08.007.
Chin C-L, Tang X, Bouchard L-S, Saha PK, Warren WS, Wehrli FW. Isolating quantum coherences in structural imaging using intermolecular double-quantum coherence MRI. Journal of magnetic resonance (San Diego, Calif : 1997). 2003 Dec;165(2):309–14.
Chin, Chih-Liang, et al. “Isolating quantum coherences in structural imaging using intermolecular double-quantum coherence MRI.Journal of Magnetic Resonance (San Diego, Calif. : 1997), vol. 165, no. 2, Dec. 2003, pp. 309–14. Epmc, doi:10.1016/j.jmr.2003.08.007.
Chin C-L, Tang X, Bouchard L-S, Saha PK, Warren WS, Wehrli FW. Isolating quantum coherences in structural imaging using intermolecular double-quantum coherence MRI. Journal of magnetic resonance (San Diego, Calif : 1997). 2003 Dec;165(2):309–314.
Journal cover image

Published In

Journal of magnetic resonance (San Diego, Calif. : 1997)

DOI

EISSN

1096-0856

ISSN

1090-7807

Publication Date

December 2003

Volume

165

Issue

2

Start / End Page

309 / 314

Related Subject Headings

  • Surgery, Computer-Assisted
  • Signal Processing, Computer-Assisted
  • Radius
  • Quantum Theory
  • Magnetic Resonance Imaging
  • Humans
  • Feasibility Studies
  • Crystallography
  • Biophysics
  • Algorithms