Rhodium-catalyzed asymmetric cyclization/hydroboration of 1,6-enynes.
Publication
, Journal Article
Kinder, RE; Widenhoefer, RA
Published in: Organic letters
May 2006
[reaction: see text] Reaction of enyne 1 with catecholborane catalyzed by a 1:1 mixture of [Rh(COD)(2)](+)SbF(6)(-) and (S)-BINAP (5 mol %) followed by Pd-catalyzed arylation with p-IC(6)H(4)CF(3) gave benzylidenecyclopentane 5 in 65% yield with 88% ee. Rhodium-catalyzed asymmetric cyclization/hydroboration followed either by Pd-catalyzed arylation or by oxidation was applied to the synthesis of a number of chiral, nonracemic carbocycles and heterocycles.
Duke Scholars
Published In
Organic letters
DOI
EISSN
1523-7052
ISSN
1523-7060
Publication Date
May 2006
Volume
8
Issue
10
Start / End Page
1967 / 1969
Related Subject Headings
- Organic Chemistry
- 34 Chemical sciences
- 03 Chemical Sciences
Citation
APA
Chicago
ICMJE
MLA
NLM
Kinder, R. E., & Widenhoefer, R. A. (2006). Rhodium-catalyzed asymmetric cyclization/hydroboration of 1,6-enynes. Organic Letters, 8(10), 1967–1969. https://doi.org/10.1021/ol052986t
Kinder, Robert E., and Ross A. Widenhoefer. “Rhodium-catalyzed asymmetric cyclization/hydroboration of 1,6-enynes.” Organic Letters 8, no. 10 (May 2006): 1967–69. https://doi.org/10.1021/ol052986t.
Kinder RE, Widenhoefer RA. Rhodium-catalyzed asymmetric cyclization/hydroboration of 1,6-enynes. Organic letters. 2006 May;8(10):1967–9.
Kinder, Robert E., and Ross A. Widenhoefer. “Rhodium-catalyzed asymmetric cyclization/hydroboration of 1,6-enynes.” Organic Letters, vol. 8, no. 10, May 2006, pp. 1967–69. Epmc, doi:10.1021/ol052986t.
Kinder RE, Widenhoefer RA. Rhodium-catalyzed asymmetric cyclization/hydroboration of 1,6-enynes. Organic letters. 2006 May;8(10):1967–1969.
Published In
Organic letters
DOI
EISSN
1523-7052
ISSN
1523-7060
Publication Date
May 2006
Volume
8
Issue
10
Start / End Page
1967 / 1969
Related Subject Headings
- Organic Chemistry
- 34 Chemical sciences
- 03 Chemical Sciences